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| Chen,H., Schuster,M.C., Sfyroera,G., Geisbrecht,B.V. and Lambris,J.D. (2008). Solution insights into the structure of the Efb/C3 complement inhibitory complex as revealed by lysineacetylation and mass spectrometry. Journal of the American Society for Mass Spectrometry, 19 (1):55-65 |
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| Chiu, R.L., Mulakala, C., Lambris, J.D., Kaznessis Y.N. (2008). Development of a new pharmacophore model that discriminates active compstatin analogs. Chem Biol Drug Des. 72 (4):249-256 |
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| Fleming,S.D., Phillips,L.M. and Lambris,J.D. (2008). Complement component C5a mediates hemorrhage-induced intestinal damage. J Surg Res, 150:196-203 |
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| Goto, M. Tjernberg, J., Dufrane, D., Elgue, G., Brandhorst, D. Ekdahl, K. N., Brandhorst, H., Wennberg, L., Kurokawa, Y., Satomi, S., Lambris, J.D., Gianello, P., Korsgren, O., Nilsson, B. (2008). Dissecting and instant blood-mediated inflammatory reaction in islet xenotransplantation. Xenotransplantation. 15 (4):225-234 |
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| Hadziahmetovic,M., Dentchev,T., Song,Y., Haddad,N., He,X.N., Hahn,P., Pratico,D., Wen,R., Harris,Z.L., Lambris,J.D., Beard,J. and Dunaief,J.L. (2008). Ceruloplasmin/hephaestin knockout mice model morphologic and molecular features of AMD. Investigative Ophthalmology & Visual Science, 49 (6):2728-2736 |
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| Hamad,O.A., Eldahi,K.N., Nilsson,P.H., Andersson,J., Magotti,P., Lambris,J.D. and Nilsson,B. (2008). Complement activation triggered by chondroitin sulfare released by thrombin receptoractivated platelets. Journal of Thromb Haemost, 6 (8):1413-1421 |
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| Haspel,N., Ricklin,D., Geisbrecht,B.V., Kavraki,L.E. and Lambris,J.D. (2008). Electrostatic Contributions Drive the Interaction Between Staphylococcus aureus Protein Efb-C and its Complement Target C3d. Protein Science, 17:1894-1906. Additional Links: Supplementary Material |
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| Hellerud,B.C., Stenvik,J., Espevik,T., Lambris,J.D., Mollnes,T.E. and Brandtzaeg,P. (2008). The stages of meningococcal sepsis simulated in vitro with emphasis on complement and Toll-like receptor activation. Infection and Immunity, 76 (9):4183-4189 |
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| Kambas,K., Markiewski,M.M, Pneumatikos,I.A., Rafail,S., Theodorou,V., Konstantonis,D., Kourtzelis,I., Doumas,M., Magotti,P., DeAngelis,R.A., Lambris,J.D. and Ritis,K. (2008). C5a and TNF-{alpha} up-regulate the expression of tissue factor in intra-alveolar neutrophils of patients with the acute respiratory distress syndrom. Journal of Immunology, 180:7368-7375 |
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| Markiewski,M.M, DeAngelis,R.A., Benencia,F., Ricklin-Lichtsteiner,S.K., Koutoulaki,A., Gerard,C., Coukos,G. and Lambris,J.D. (2008). Modulation of the anti-tumor immune response by complement. Nature Immunology, 9 (11):1225-1235. Additional Links: Supplementary Information, Nature Immunology News & Views, Nature Biotechnology News & Views, Nature Cancer Reviews Highlight |
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| Ricklin,D., Ricklin-Lichtsteiner,S.K., Markiewski,M.M, Geisbrecht,B.V. and Lambris,J.D. (2008). Cutting edge: staphylococcus aureus extracellular fibrinogen -binding protein inhibits the interaction of C3d with complement receptor 2. Journal of Immunology. 181: 7463-7467 |
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| Rynkowski,M.A., Kim.G.H., Garrett,M.C., Zacharia,B.E., Otten,M.L., Sosunov,S.A., Komotar,R.J., Hassid,B.G., Ducruet,A.F., Lambris,J.D., Connolly,E.S. (2008). C3a receptor antagonist attenuates brain injury after intracerebral hemorrhage. J Cereb Blood Flow Metab. 1-10 |
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| Saethre.M., Schreiner,O., Lambris,J.D., Magotti,P., Haraldsen,G., Seebach,J.D. and Mollnes,T.E. (2008). Cytokine secretion depends on Galalpha (1,3) Gal expression in a pig-to-human whole blood model. Journal of Immunology, 180:6346-6353 |
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| Schuster,M.C., Ricklin,D., Papp,K., Molnar,K.S., Coales,S.J., Hamuro,Y., Sfyroera,G., Chen,H., Winters,M.S. and Lambris,J.D. (2008). Dynamic structural changes during complement C3 activation analyzed by hydrogen/deuterium exchange mass spectrometry. Molecular Immunology, 45 (11):3142-3151 |
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| Tjernberg,J., Ekdahl,K.N., Lambris,J.D., Korsgren,O. and Nilsson,B. (2008). Acute antibody-mediated complement activation mediates lysis of pancreatic islets cells and may cause tissue loss in clinical islet transplantation. Transplantation, 85 (8):1193-1199 |
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| Zucchetti,I., Marino,R., Pinto,M.R., Lambris,J.D., Du Pasquier,L. and De Santis,R. (2008). ciCD94-1, an ascidian multipurpose C-type lectin-like receptor expressed in Ciona intestinalis hemocytes and larval neural structures. Differentiation, 76 (3):267-282 |
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| Hammel,M., Sfyroera,G., Ricklin,D., Magotti,P., Lambris,J.D. and Geisbrecht,B.V. (2007). A structural basis for complement inhibition by Staphylococcus aureus. Nature Immunology, 8 (4):430-437. Additional Links: Science Editor's Choice |
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| Hammel,M., Sfyroera,G., Pyrpassopoulos,S., Ricklin,D., Ramyar,K.X., Pop,M., Jin,Z., Lambris,J.D. and Geisbrecht,B.V. (2007). Characterization of Ehp, a secreted complement inhibitory protein from Staphylococcus aureus. Journal of Biological Chemistry, 282 (41):30051-30061 |
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| Janssen,B.J.C., Halff,E.F., Lambris,J.D. and Gros,P. (2007). Structure of compstatin in complex with complement component C3c reveals a new mechanism of complement inhibition. Journal of Biological Chemistry, 282 (40):29241-29247 |
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| Jozsi,M., Oppermann,M., Lambris,J.D. and Zipfel,P.F. (2007). The C-terminus of complement factor H is essential for host cell protection. Molecular Immunology, 44 (10):2697-2706 |
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| Lappegard,K.T., Bergseth,G., Riesenfeld,J., Pharo,A., Magotti,P., Lambris,J.D. and Mollnes,T.E. (2007). The artificial surface-induced whole blood inflammatory reaction revealed by increases in a series of chemokines and growth factors is largely complement dependent. J Biomed Mater Res. 87A (1):129-135 |
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| Miwa,T., Zhou,L., Tudoran,R., Lambris,J.D., Madaio,M.P., Nangaku,M., Molina,H. and Song,W.C. (2007). DAF/Crry double deficiency in mice exacerbates nephrotoxic serum-induced proteinuria despite markedly reduced systemic complement activity. Molecular Immunology, 44 (1-3):139-146 |
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| Montalvo,V., Chan,C.C., Gery,I., Campos,M.M., Wawrousek,E.F., Bush,R.A. and Lambris,J.D. (2007). Complement deposits on ocular tissues adjacent to sites of inflammation. Current Eye Research, 32 (11):917-922 |
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| Mulakala,C., Lambris,J.D. and Kaznessis,Y. (2007). A simple, yet highly accurate, QSAR model captures the complement inhibitory activity of compstatin. Bioorganic & Medicinal Chemistry, 15 (4):1638-1644 |
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| Nielsen,E.W., Waage,C., Fure,H., Brekke,O.L., Sfyroera,G., Lambris,J.D. and Mollnes,T.E. (2007). Effect of supraphysiologic levels of C1-inhibitor on the classical, lectin and alternative pathways of complement. Molecular Immunology, 44 (8):1819-1826 |
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| Pedersen,E.D., Aass,H.C.D., Rootwelt,T., Fung,M., Lambris,J.D. and Mollnes,T.E. (2007). CD59 efficiently protects human NT2-N neurons against complement-mediated damage. Scandinavian Journal of Immunology, 66 (2-3):345-351 |
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| Smith,R.J.H., Alexander,J., Barlow,P.N., Botto,M., Cassavant,T.L., Cook,H.T., de Cordoba,S.R., Hageman,G.S., Jokiranta,T.S., Kimberling,W.J., Lambris,J.D., Lanning,L.D., Levidiotis,V., Licht,C., Lutz,H.U., Meri,S., Pickering,M.C., Quigg,R.J., Rops,A.L., Salant,D.J., Sethi,S., Thurman,J.M., Tully,H.F., Tully,S.P., van der Vlag,J., Walker,P.D., Wurzner,R. and Zipfel,P.F. (2007). New approaches to the treatment of dense deposit disease. Journal of the American Society of Nephrology, 18 (9):2447-2456 |
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| Stevens,B., Allen,N.J., Vazquez,L.E., Howell,G.R., Christopherson,K.S., Nouri,N., Micheva,K.D., Mehalow,A.K., Huberman,A.D., Stafford,B., Sher,A., Litke,A.M., Lambris,J.D., Smith,S.J., John,S.W.M. and Barres,B.A. (2007). The classical complement cascade mediates CNS synapse elimination. Cell, 131 (6):1164-1178. Additional Links: Science News of The Week, Cell Preview |
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| Tamamis,P., Skourtis,S.S., Morikis,D., Lambris,J.D. and Archontis,G. (2007). Conformational analysis of compstatin analogues with molecular dynamics simulations in explicit water. Journal of Molecular Graphics & Modelling, 26 (2):571-580 |
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| Thurman,J.M., Lenderink,A.M., Royer,P.A., Coleman,K.E., Zhou,J., Lambris,J.D., Nemenoff,R.A., Quigg,R.J. and Holers,V.M. (2007). C3a is required for the production of CXC chemokines by tubular epithelial cells after renal ishemia/reperfusion. Journal of Immunology, 178 (3):1819-1828 |
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| Zhang,X.H., Kimura,Y., Fang,C.Y., Zhou,L., Sfyroera,G., Lambris,J.D., Wetsel,R., Miwa,T. and Song,W.C. (2007). Regulation of Toll-like receptor-mediated inflammatory response by complement in vivo. Blood, 11 (1):228-235 |
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| Anderson,A.L., Sporici,R., Lambris,J., LaRosa,D. and Levinson,A.I. (2006). Pathogenesis of B-cell superantigen-induced immune complex-mediated inflammation. Infection and Immunity, 74 (2):1196-1203 |
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| Droulin,S.M., Sinha,M., Sfyroera,G., Lambris,J.D. and Wetsel,R.A. (2006). A protective role for the fifth complement component (C5) in allergic airway disease. American Journal of Respiratory and Critical Care Medicine, 173 (8):852-857 |
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| Huber-Lang,M., Sarma,J.V., Zetoune,F.S., Rittirsch,D., Neff,T.A., McGuire,S.R., Lambris,J.D., Warner,R.L., Flierl,M.A., Hoesel,L.M., Gebhard,F., Younger,J.G., Drouin,S.M., Wetsel,R.A. and Ward,P.A. (2006). Generation of C5a in the absence of C3: a new complement activation pathway. Nature Medicine, 12 (6):682-687 |
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| Janssen,B.J.C., Christodoulidou,A., McCarthy,A., Lambris,J.D. and Gros,P. (2006). Structure of C3b reveals conformational changes that underlie complement activity. Nature, 444 (7116):213-216. Additional Links: News & Views |
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| Katragadda,M., Magotti,P., Sfyroera,G. and Lambris,J.D. (2006). Hydrophobic effect and hydrogen bonds account for the improved activity of a complement inhibitor, compstatin. Journal of Medicinal Chemistry, 49 (15):4616-4622 |
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| Katragadda,M. and Lambris,J.D. (2006). Expression of compstatin in Escherichia coli: Incorporation of unnatural amino acids enhances its activity. Protein Expression and Purification, 47 (1):289-295 |
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| Kohl,J., Balder,R., Lewkowich,I., Pandey,M.K., Hawlisch,H., Wang,L.H., Herman,N., Sproles,A., Best,J., Zwirner,J., Whitsett,J.A., Lambris,J.D. and Wills-Karp,M. (2006). A regulatory role for the C5a anaphylatoxin on type 2 immunity in experimental asthma.
Journal of Clininical Investigation, 116:783-96. Additional Links: Commentary |
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| Melillo,D., Sfyroera,G., De Santis,R., Graziano,R., Marino,R., Lambris,J.D. and Pinto,M.R. (2006). First identification of a chemotactic receptor in an invertebrate species: Structural and functional characterization of Ciona intestinalis C3a receptor. Journal of Immunology, 177 (6):4132-4140 |
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| Nozaki,M., Raisler,B.J., Sakurai,E., Sarma,J.V., Barnum,S.R., Lambris,J.D., Chen,Y., Zhang,K., Ambati,B.K., Baffi,J.Z. and Ambati,J. (2006). Drusen complement components C3a and C5a promote choroidal neovascularization. Proceedings of the National Academy of Sciences of the United States of America, 103 (7):2328-2333 |
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| Ritis,K., Doumas,M., Mastellos,D., Micheli,A., Giaglis,S., Magotti,P., Rafail,S., Kartalis,G., Sideras,P. and Lambris,J.D. (2006). A novel c5a receptor-tissue factor cross-talk in neutrophils links innate immunity to coagulation pathways. Journal of Immunology, 177 (7):4794-4802 |
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| Soulika,A.M., Holland,M.C.H., Sfyroera,G., Sahu,A. and Lambris,J.D. (2006). Compstatin inhibits complement activation by binding to the beta-chain of complement factor 3. Molecular Immunology, 43 (12):2023-2029 |
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| Andersson,J., Ekdahl,K.N., Lambris,J.D. and Nilsson,B. (2005). Binding of C3 fragments on top of adsorbed plasma proteins during complement activation on a model biomaterial surface. Biomaterials, 26 (13):1477-1485 |
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| Bao,L.H., Osawe,I., Puri,T., Lambris,J.D., Haas,M. and Quigg,R.J. (2005). C5a promotes development of experimental lupus nephritis which can be blocked with a specific receptor antagonist. European Journal of Immunology, 35 (8):2496-2506 |
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| DeAngelis,R.A., Markiewski,M.M., Taub,R. and Lambris,J.D. (2005). A high-fat diet impairs liver regeneration in C57BL/6 mice through overexpression of the NF-kappa B inhibitor, I kappa B alpha. Hepatology, 42 (5):1148-1157. Additional Links: Editorial |
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| Lappegard,K.T., Riesenfeld,J., Brekke,O.L., Bergseth,G., Lambris,J.D. and Mollnes,T.E. (2005). Differential effect of heparin coating and complement inhibition on artificial surface-induced eicosanoid production. Annals of Thoracic Surgery, 79 (3):917-923 |
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| Li,S., Boackle,S.A., Holers,V.M., Lambris,J.D. and Blatteis,C.M. (2005). Complement component C5a is integral to the febrile response of mice to lipopolysaccharide. Neuroimmunomodulation , 12 (2):67-80 |
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| Liu,J.N., Miwa,T., Hilliard,B., Chen,Y.H., Lambris,J.D., Wells,A.D. and Song,W.C. (2005). The complement inhibitory protein DAF (CD55) suppresses T cell immunity in vivo. Journal of Experimental Medicine, 201 (4):567-577 |
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| Mallik,B., Katragadda,M., Spruce,L.A., Carafides,C., Tsokos,C.G., Morikis,D. and Lambris,J.D. (2005). Design and NMR characterization of active analogues of compstatin containing non-natural amino acids. J Med. Chem., 48 (1):274-286 |
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| Pappas,I.S., Lambris,J.D., Vizirianakis,I.S., Winters,M.S. and Tsiftsoglou,A.S. (2005). Mechanisms of action of differentiation inducers: Detection of inducer binding protein(s) in murine erythroleukemia cells. Oncology Research, 15 (1):21-37 |
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| Sfyroera,G., Katragadda,M., Morikis,D., Isaacs,S.N. and Lambris,J.D. (2005). Electrostatic modeling predicts the activities of orthopoxvirus complement control proteins. Journal of Immunology, 174 (4):2143-2151 |
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| Strey,C.W., Winters,M.S., Markiewski,M.M. and Lambris,J.D. (2005). Partial hepatectomy induced liver proteome changes in mice. Proteomics, 5 (1):318-325 |
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| Winters,M.S., Spellman,D.S. and Lambris,J.D. (2005). Solvent accessibility of native and hydrolyzed human complement protein 3 analyzed by hydrogen/deuterium exchange and mass spectrometry. Journal of Immunology, 174 (6):3469-3474 |
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| Bell,E., Shamim,M., Whitbeck,J.C., Sfyroera,G., Lambris,J.D. and Isaacs,S.N. (2004). Antibodies against the extracellular enveloped virus B5R protein are mainly responsible for the EEV neutralizing capacity of vaccinia immune globulin. Virology, 325 (2):425-431 |
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| Holland,M.C.H. and Lambris,J.D. (2004). A functional C5a anaphylatoxin receptor in a teleost species. Journal of Immunology, 172 (1):349-355 |
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| Katragadda,M., Morikis,D. and Lambris,J.D. (2004). Thermodynamic studies on the interaction of the third complement component and its inhibitor, compstatin. Journal of Biological Chemistry, 279 (53):54987-54995 |
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| Kim,A.H.J., Dimitriou,I.D., Holland,M.C.H., Mastellos,D., Mueller,Y.M., Altman,J.D., Lambris,J.D. and Katsikis,P.D. (2004). Complement C5a receptor is essential for the optimal generation of antiviral CD8(+) T cell responses. Journal of Immunology, 173 (4):2524-2529 |
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| Klepeis,J.L., Floudas,C.A., Morikis,D., Tsokos,C.G. and Lambris,J.D. (2004). Design of peptide analogues with improves activity using a novel de Novo protein design approach. Industrial & Engineering Chemistry Research, 43 (14):3817-3826 |
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| Lappegard,K.T., Fung,M., Bergseth,G., Riesenfeld,J., Lambris,J.D., Videm,V. and Mollnes,T.E. (2004). Effect of complement inhibition and heparin coating on artificial surface-induced leukocyte and platelet activation. Annals of Thoracic Surgery, 77 (3):932-941 |
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| Markiewski,M.M., Mastellos,D., Tudoran,R., DeAngelis,R.A., Strey,C.W., Franchini,S., Wetsel,R.A., Erdei,A. and Lambris,J.D. (2004). C3a and C3b activation products of the third component of complement (C3) are critical for normal liver recovery after toxic injury. Journal of Immunology, 173 (2):747-754 |
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| Mastellos,D., Prechl,J., Laszlo,G., Papp,K., Olah,E., Argyropoulos,E., Franchini,S., Tudoran,R., Markiewski,M., Lambris,J.D. and Erdei,A. (2004). Novel monoclonal antibodies against mouse C3 interfering with complement activation: description of fine specificity and applications to various immunoassays. Molecular Immunology, 40 (16):1213-1221 |
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| Morikis,D. and Lambris,J.D. (2004). The electrostatic nature of C3d-Complement receptor 2 association. Journal of Immunology, 172 (12):7537-7547 |
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| Park,J.W., Taube,C., Joetham,A., Takeda,K., Kodama,T., Dakhama,A., McConville,G., Allen,C.B., Sfyroera,G., Shultz,L.D., Lambris,J.D., Giclas,P.C., Holers,V.M. and Gelfand,E.W. (2004). Complement activation is critical to airway hyperresponsiveness after acute ozone exposure. American Journal of Respiratory and Critical Care Medicine, 169 (6):726-732 |
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| Sewell,D.L., Nacewicz,B., Liu,F., Macvilay,S., Erdei,A., Lambris,J.D., Sandor,M. and Fabry,Z. (2004). Complement C3 and C5 play critical roles in traumatic brain cryoinjury: blocking effects on neutrophil extravasation by C5a receptor antagonist. Journal of Neuroimmunology, 155 (1-2):55-63 |
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| Strey,C.W., Spellman,D., Stieber,A., Gonatas,J.O., Wang,X.S., Lambris,J.D. and Gonatas,N.K. (2004). Dysregulation of stathmin, a microtubule-destabilizing protein, and up-regulation of Hsp25, Hsp27, and the antioxidant peroxiredoxin 6 in a mouse model of familial amyotrophic lateral sclerosis. American Journal of Pathology, 165 (5):1701-1718 |
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| Fleming,S.D., Mastellos,D., Karpel-Massler,G., Shea-Donohue,T., Lambris,J.D. and Tsokos,G.C. (2003). C5a causes limited, polymorphonuclear cell-independent, mesenteric ischemia/reperfusion-induced injury. Clinical Immunology, 108 (3):263-273 |
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| Girardi,G., Berman,J., Redecha,P., Spruce,L., Thurman,J.M., Kraus,D., Hollman,T.J., Casali,P., Caroll,M.C., Wetsel,R.A., Lambris,J.D., Holers,V.M. and Salmon,J.E. (2003). Complement C5a receptors and neutrophils mediate fetal injury in the antiphospholipid syndrome. Journal of Clinical Investigation, 112 (11):1644-1654 |
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| Isaacs,S.N., Argyropoulos,E., Sfyroera,G., Mohammad,S. and Lambris,J.D. (2003). Restoration of complement-enhanced neutralization of vaccinia virus virions by novel monoclonal antibodies raised against the vaccinia virus complement control protein. Journal of Virology, 77 (15):8256-8262 |
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| Kazantzi,A., Sfyroera,G., Holland,M.C.H., Lambris,J.D. and Zarkadis,L.K. (2003). Molecular cloning of the beta subunit of complement component eight of rainbow trout. Developmental and Comparative Immunology, 27 (3):167-174 |
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| Kimura,Y., Madhavan,M., Call,M.K., Santiago,W., Tsonis,P.A., Lambris,J.D. and Del Rio-Tsonis,K. (2003). Expression of complement 3 and complement 5 in newt limb and lens regeneration. Journal of Immunology, 170 (5):2331-2339. Additional Links: In This Issue |
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| Klepeis,J.L., Floudas,C.A., Morikis,D., Tsokos,C.G., Argyropoulos,E., Spruce,L. and Lambris,J.D. (2003). Integrated computational and experimental approach for lead optimization and design of compstatin variants with improved activity. Journal of the American Chemical Society, 125 (28):8422-8423. Additional Links: Supplementary Information |
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| Mallik,B., Lambris,J.D. and Morikis,D. (2003). Conformational interconversion in compstatin probed with molecular dynamics simulations. Proteins-Structure Function and Genetics, 53 (1):130-141 |
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| Mullick,J., Bernet,J., Singh,A.K., Lambris,J.D. and Sahu,A. (2003). Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) open reading frame 4 protein (Kaposica) is a functional homolog of complement control proteins. Journal of Virology, 77 (6):3878-3881 |
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| Pinto,M.R., Chinnici,C.M., Kimura,Y., Melillo,D., Marino,R., Spruce,L.A., De Santis,R., Parrinello,N. and Lambris,J.D. (2003). CiC3-1a-mediated chemotaxis in the deuterostome invertebrate Ciona intestinalis (Urochordata). Journal of Immunology, 171 (10):5521-5528 |
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| Reca,R., Mastellos,D., Majka,M., Marquez,L., Ratajczak,J., Franchini,S., Glodek,A., Honczarenko,M., Spruce,L.A., Janowska-Wieczorek,A., Lambris,J.D. and Ratajczak,M.Z. (2003). Functional receptor for C3a anaphylatoxin is expressed by normal hematopoietic stem/progenitor cells, and C3a enhances their homing-related responses to SDF-1. Blood, 101 (10):3784-3793 |
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| Riedemann,N.C., Neff,T.A., Guo,R.F., Bernacki,K.D., Laudes,I.J., Sarma,J.V., Lambris,J.D. and Ward,P.A. (2003). Protective effects of IL-6 blockade in sepsis are linked to reduced C5a receptor expression. Journal of Immunology, 170 (1):503-507 |
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| Sahu,A., Morikis,D. and Lambris,J.D. (2003). Compstatin, a peptide inhibitor of complement, exhibits species-specific binding to complement component C3. Molecular Immunology, 39 (10):557-566 |
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| Soulika,A.M., Morikis,D., Sarrias,M.R., Roy,M., Spruce,L.A., Sahu,A. and Lambris,J.D. (2003). Studies of structure-activity relations of complement inhibitor compstatin. Journal of Immunology, 171 (4):1881-1890 |
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| Strey,C.W., Markiewski,M., Mastellos,D., Tudoran,R., Spruce,L.A., Greenbaum,L.E. and Lambris,J.D. (2003). The proinflammatory mediators C3a and C5a are essential for liver regeneration. Journal of Experimental Medicine, 198 (6):913-923 |
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| Suresh,M., Molina,H., Salvato,M.S., Mastellos,D., Lambris,J.D. and Sandor,M. (2003). Complement component 3 is required for optimal expansion of CD8 T cells during a systemic viral infection. Journal of Immunology, 170 (2):788-794 |
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| Barilla-LaBarca,M.L., Liszewski,M.K., Lambris,J.D., Hourcade,D. and Atkinson,J.P. (2002). Role of membrane cofactor protein (CD46) in regulation of C4b and C3b deposited on cells. Journal of Immunology, 168 (12):6298-6304 |
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| Huber-Lang,M.S., Riedeman,N.C., Sarma,J.V., Younkin,E.M., McGuire,S.R., Laudes,I.J., Lu,K.T., Guo,R.F., Neff,T.A., Padgaonkar,V.A., Lambris,J.D., Spruce,L., Mastellos,D., Zetoune,F.S. and Ward,P.A. (2002). Protection of innate immunity by C5aR antagonist in septic mice. Faseb Journal, 16 (12):1567-1574 |
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| Laudes,I.J., Chu,J.C., Huber-Lang,M., Guo,R.F., Riedemann,N.C., Sarma,J.V., Mahdi,F., Murphy,H.S., Speyer,C., Lu,K.T., Lambris,J.D., Zetoune,F.S. and Ward,P.A. (2002). Expression and function of C5a receptor in mouse microvascular endothelial cells. Journal of Immunology, 169 (10):5962-5970 |
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| Lubinski,J.M., Jiang,M., Hook,L., Chang,Y., Sarver,C., Mastellos,D., Lambris,J.D., Cohen,G.H., Eisenberg,R.J. and Friedman,H.M. (2002). Herpes simplex virus type 1 evades the effects of antibody and complement in vivo. Journal of Virology, 76 (18):9232-9241 |
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| Marino,R., Kimura,Y., De Santis,R., Lambris,J.D. and Pinto,M.R. (2002). Complement in urochordates: cloning and characterization of two C3-like genes in the ascidian Ciona intestinalis. Immunogenetics, 53 (12):1055-1064 |
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| Molina,H., Miwa,T., Zhou,L., Hilliard,B., Mastellos,D., Maldonado,M.A., Lambris,J.D. and Song,W.C. (2002). Complement-mediated clearance of erythrocytes: mechanism and delineation of the regulatory roles of Crry and DAF. Blood, 100 (13):4544-4549 |
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| Mollnes,T.E., Brekke,O.L., Fung,M., Fure,H., Christiansen,D., Bergseth,G., Videm,V., Lappegard,K.T., Kohl,J. and Lambris,J.D. (2002). Essential role of the C5a receptor in E-coli-induced oxidative burst and phagocytosis revealed by a novel lepirudin-based human whole blood model of inflammation. Blood, 100 (5):1869-1877 |
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| Morikis,D., Roy,M., Sahu,A., Troganis,A., Jennings,P.A., Tsokos,G.C. and Lambris,J.D. (2002). The structural basis of compstatin activity examined by structure-function-based design of peptide analogs and NMR. Journal of Biological Chemistry, 277 (17):14942-14953. Additional Links: Supplementary Information |
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| Riedemann,N.C., Guo,R.F., Neff,T.A., Laudes,I.J., Keller,K.A., Sarma,V.J., Markiewski,M.M., Mastellos,D., Strey,C.W., Pierson,C.L., Lambris,J.D., Zetoune,F.S. and Ward,P.A. (2002). Increased C5a receptor expression in sepsis. Journal of Clinical Investigation, 110 (1):101-108 |
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| Rux,A.H., Lou,H., Lambris,J.D., Friedman,H.M., Eisenberg,R.J. and Cohen,G.H. (2002). Kinetic analysis of glycoprotein C of herpes simplex virus types 1 and 2 binding to heparin, heparan sulfate, and complement component C3b. Virology, 294 (2):324-332 |
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| Vasta,G.R. and Lambris,J.D. (2002). Innate immunity in the Aegean: ancient pathways for today's survival. Developmental and Comparative Immunology, 26 (3):217-225 |
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| Wyss-Coray,T., Yan,F.R., Lin,A.H.T., Lambris,J.D., Alexander,J.J., Quigg,R.J. and Masliah,E. (2002). Prominent neurodegeneration and increased plaque formation in complement-inhibited Alzheimer's mice. Proceedings of the National Academy of Sciences of the United States of America, 99 (16):10837-10842 |
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| Franchini,S., Zarkadis,I.K., Sfyroera,G., Sahu,A., Moore,W.T., Mastellos,D., LaPatra,S.E. and Lambris,J.D. (2001). Cloning and purification of the rainbow trout fifth component of complement (C5). Developmental and Comparative Immunology, 25 (5-6):419-430 |
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| Guthridge,J.M., Rakstang,J.K., Young,K.A., Hinshelwood,J., Aslam,M., Robertson,A., Gipson,M.G., Sarrias,M.R., Moore,W.T., Meagher,M., Karp,D., Lambris,J.D., Perkins,S.J. and Holers,V.M. (2001). Structural studies in solution of the recombinant N-terminal pair of short consensus/complement repeat domains of complement receptor type 2 (CR2/CD21) and interactions with its ligand C3dg. Biochemistry, 40 (20):5931-5941 |
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| Guthridge,J.M., Young,K., Gipson,M.G., Sarrias,M.R., Szakonyi,G., Chen,X.J.S., Malaspina,A., Donoghue,E., James,J.A., Lambris,J.D., Moir,S.A., Perkins,S.J. and Holers,V.M. (2001). Epitope mapping using the X-ray crystallographic structure of complement receptor type 2 (CR2)/CD21: Identification of a highly inhibitory monoclonal antibody that directly recognizes the CR2-C3d interface. Journal of Immunology, 167 (10):5758-5766 |
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| Mastellos,D., Papadimitriou,J.C., Franchini,S., Tsonis,P.A. and Lambris,J.D. (2001). A novel role of complement: Mice deficient in the fifth component of complement (C5) exhibit impaired liver regeneration. Journal of Immunology, 166 (4):2479-2486 |
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| Sarrias,M.R., Franchini,S., Canziani,G., Argyropoulos,E., Moore,W.T., Sahu,A. and Lambris,J.D. (2001). Kinetic analysis of the interactions of complement receptor 2 (CR2, CD21) with its ligands C3d, iC3b, and the EBV glycoprotein gp350/220. Journal of Immunology, 167 (3):1490-1499. Additional Links: Biacore PDF |
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| Solvik,U.O., Haraldsen,G., Fiane,A.E., Boretti,E., Lambris,J.D., Fung,M., Thorsby,E. and Mollnes,T.E. (2001). Human serum-induced expression of E-selectin on porcine aortic endothelial cells in vitro is totally complement mediated. Transplantation, 72 (12):1967-1973 |
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| Zarkadis,I.K., Sarrias,M.R., Sfyroera,G., Sunyer,J.O. and Lambris,J.D. (2001). Cloning and structure of three rainbow trout C3 molecules: a plausible explanation for their functional diversity. Developmental and Comparative Immunology, 25 (1):11-24 |
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| Fiane,A.E., Videm,V., Lambris,J.D., Geiran,O.R., Svennevig,J.L. and Mollnes,T.E. (2000). Modulation of fluid-phase complement activation inhibits hyperacute rejection in a porcine-to-human xenograft model. Transplantation Proceedings, 32 (5):899-900 |
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| Friedman,H.M., Wang,L.Y., Pangburn,M.K., Lambris,J.D. and Lubinski,J. (2000). Novel mechanism of antibody-independent complement neutralization of herpes simplex virus type 1. Journal of Immunology, 165 (8):4528-4536 |
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| Sahu,A., Soulika,A.M., Morikis,D., Spruce,L., Moore,W.T. and Lambris,J.D. (2000). Binding kinetics, structure-activity relationship, and biotransformation of the complement inhibitor compstatin. Journal of Immunology, 165 (5):2491-2499 |
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| Sarrias,M.R., Whitbeck,J.C., Rooney,I., Ware,C.F., Eisenberg,R.J., Cohen,G.H. and Lambris,J.D. (2000). The three HveA receptor ligands, gD, LT-alpha and LIGHT bind to distinct sites on HveA. Molecular Immunology, 37 (11):665-673 |
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| Soulika,A.M., Khan,M.M., Hattori,T., Bowen,F.W., Richardson,B.A., Hack,C.E., Sahu,A., Edmunds,L.H. and Lambris,J.D. (2000). Inhibition of heparin/protamine complex-induced complement activation by Compstatin in baboons. Clinical Immunology, 96 (3):212-221 |
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| Al-Sharif,W.Z., Sunyer,J.O., Lambris,J.D. and Smith,L.C. (1999). Sea urchin coelomocytes specifically express a homologue of the complement component C3. Journal of Immunology, 160 (5):2983-2997 |
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| Fiane,A.E., Mollnes,T.E., Videm,V., Hovig,T., Hogasen,K., Mellbye,O.J., Spruce,L., Moore,W.T., Sahu,A. and Lambris,J.D. (1999). Prolongation of ex vivo-perfused pig xenograft survival by the complement inhibitor compstatin. Transplantation Proceedings, 31 (1-2):934-935 |
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| Fiane,A.E., Mollnes,T.E., Videm,V., Hovig,T., Hogasen,K., Mellbye,O.J., Spruce,L., Moore,W.T., Sahu,A. and Lambris,J.D. (1999). Compstatin, a peptide inhibitor of C3, prolongs survival of ex vivo perfused pig xenografts. Xenotransplantation, 6 (1):52-65 |
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| Klepeis,J.L., Floudas,C.A., Morikis,D. and Lambris,J.D. (1999). Predicting peptide structures using NMR data and deterministic global optimization. Journal of Computational Chemistry , 20 (13):1354-1370 |
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| Lambris,J.D., Reid,K.B.M. and Volanakis,J.E. (1999). The evolution, structure, biology and pathophysiology of complement. Immunology Today, 20 (5):207-211 |
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| Lubinski,J., Wang,L.Y., Mastellos,D., Sahu,A., Lambris,J.D. and Friedman,H.M. (1999). In vivo role of complement-interacting domains of herpes simplex virus type 1 glycoprotein gC. Journal of Experimental Medicine, 190 (11):1637-1646 |
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| Noorchashm,H., Moore,D.J., Lieu,Y.K., Noorchashm,N., Schlachterman,A., Song,H.K., Lambris,J.D., Barker,C.F. and Naji,A. (1999). Contribution of the innate immune system to autoimmune diabetes: A role for the CR1/CR2 complement receptors. Cellular Immunology, 195 (1):75-79 |
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| Sarrias,M.R., Whitbeck,J.C., Rooney,I., Spruce,L., Kay,B.K., Montgomery,R.I., Spear,P.G., Ware,C.F., Eisenberg,R.J., Cohen,G.H. and Lambris,J.D. (1999). Inhibition of herpes simplex virus gD and lymphotoxin-alpha binding to HveA by peptide antagonists. Journal of Virology, 73 (7):5681-5687 |
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| Suny,X.J., Funk,C.D., Deng,C.J., Sahu,A., Lambris,J.D. and Song,W.C. (1999). Role of decay-accelerating factor in regulating complement activation on the erythrocyte surface as revealed by gene targeting. Proceedings of the National Academy of Sciences of the United States of America, 96 (2):628-633 |
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| Del Rio-Tsonis,K., Tsonis,P.A., Zarkadis,I.K., Tsagas,A.G. and Lambris,J.D. (1998). Expression of the third component of complement, C3, in regenerating limb blastema cells of urodeles. Journal of Immunology, 161 (12):6819-6824 |
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| Krummenacher,C., Nicola,A.V., Whitbeck,J.C., Lou,H., Hou,W.F., Lambris,J.D., Geraghty,R.J., Spear,P.G., Cohen,G.H. and Eisenberg,R.J. (1998). Herpes simplex virus glycoprotein D can bind to poliovirus receptor-related protein 1 or herpesvirus entry mediator, two structurally unrelated mediators of virus entry. Journal of Virology, 72 (9):7064-7074 |
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| Lubinski,J.M., Wang,L.Y., Soulika,A.M., Burger,R., Wetsel,R.A., Colten,H., Cohen,G.H., Eisenberg,R.J., Lambris,J.D. and Friedman,H.M. (1998). Herpes simplex virus type 1 glycoprotein gC mediates immune evasion in vivo. Journal of Virology, 72 (10):8257-8263 |
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| Morikis,D., ssa-Munt,N., Sahu,A. and Lambris,J.D. (1998). Solution structure of Compstatin, a potent complement inhibitor. Protein Science, 7 (3):619-627 |
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| Nilsson,B., Larsson,R., Hong,J., Elgue,G., Ekdahl,K.N., Sahu,A. and Lambris,J.D. (1998). Compstatin inhibits complement and cellular activation in whole blood in two models of extracorporeal circulation. Blood, 92 (5):1661-1667 |
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| Peng,T., de Leon,M.P., Novotny,M.J., Jiang,H.B., Lambris,J.D., Dubin,G., Spear,P.G., Cohen,G.H. and Eisenberg,R.J. (1998). Structural and antigenic analysis of a truncated form of the herpes simplex virus glycoprotein gH-gL complex. Journal of Virology, 72 (7):6092-6103 |
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| Sahu,A., Isaacs,S.N., Soulika,A.M. and Lambris,J.D. (1998). Interaction of vaccinia virus complement control protein with human complement proteins: Factor I-mediated degradation of C3b to iC3b(1) inactivates the alternative complement pathway. Journal of Immunology , 160 (11):5596-5604 |
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| Sunyer,J.O., Zarkadis,I., Sarrias,M.R., Hansen,J.D. and Lambris,J.D. (1998). Cloning, structure, and function of two rainbow trout Bf molecules. Journal of Immunology, 161 (8):4106-4114 |
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| Kostavasil,I., Sahu,A., Friedman,H.M., Eisenberg,R.J., Cohen,G.H. and Lambris,J.D. (1997). Mechanism of complement inactivation by glycoprotein C of herpes simplex virus. Journal of Immunology, 158 (4):1763-1771 |
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| Sunyer,J.O., Tort,L. and Lambris,J.D. (1997). Structural C3 diversity in fish - Characterization of five forms of C3 in the diploid fish Spans aurata. Journal of Immunology, 158 (6):2813-2821 |
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| Sunyer,J.O., Tort,L. and Lambris,J.D. (1997). Diversity of the third form of complement, C3, in fish: Functional characterization of five forms of C3 in the diploid fish Sparus aurata. Biochemical Journal, 326:877-881 |
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| Tolnay,M., Lambris,J.D. and Tsokos,G.C. (1997). Transcriptional regulation of the complement receptor 2 gene: Role of a heterogeneous nuclear ribonucleoprotein. Journal of Immunology, 159 (11):5492-5501 |
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| Whitbeck,J.C., Peng,C., Lou,H., Xu,R.L., Willis,S.H., Deleon,M.P., Peng,T., Nicola,A.V., Montgomery,R.I., Warner,M.S., Soulika,A.M., Spruce,L.A., Moore,W.T., Lambris,J.D., Spear,P.G., Cohen,G.H. and Eisenberg,R.J. (1997). Glycoprotein D of herpes simplex virus (HSV) binds directly to HVEM, a member of the tumor necrosis factor receptor superfamily and a mediator of HSV entry. Journal of Virology, 71 (8):6083-6093 |
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| Zarkadis,I.K., Omigbodun,A., Forson,A., Ziolkiewicz,P., Kinoshita,T., Lambris,J.D. and Coutifaris,C. (1997). Differentiation-dependent changes in human trophoblast expression of decay-accelerating factor are modulated by 3',5' cyclic adenosine monophosphate. Journal of the Society for Gynecologic Investigation, 4 (1):47-53 |
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| Friedman,H.M., Wang,L.Y., Fishman,N.O., Lambris,J.D., Eisenberg,R.J., Cohen,G.H. and Lubinski,J. (1996). Immune evasion properties of herpes simplex virus type 1 glycoprotein gC. Journal of Virology, 70 (7):4253-4260 |
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| Kozlowski,L.M., Soulika,A.M., Silverman,G.J., Lambris,J.D. and Levinson,A.I. (1996). Complement activation by a B cell superantigen. Journal of Immunology, 157 (3):1200-1206 |
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| Lambris,J.D., Lao,Z., Oglesby,T.J., Atkinson,J.P., Hack,C.E. and Becherer,J.D. (1996). Dissection of CR1, factor H, membrane cofactor protein, and factor B binding and functional sites in the third complement component. Journal of Immunology, 156 (12):4821-4832 |
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| Moore,D.J. and Lambris,J.D. (1996). Mass spectrometric analysis of the activation products of the thrid component of complement. Techniques in Protein Chemistry VII Academic Press, 7:81-91 |
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| Rux,A.H., Moore,W.T., Lambris,J.D., Abrams,W.R., Peng,C., Friedman,H.M., Cohen,G.H. and Eisenberg,R.J. (1996). Disulfide bond structure determination and biochemical analysis of glycoprotein C from herpes simplex virus. Journal of Virology, 70 (8):5455-5465 |
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| Sahu,A., Kay,B.K. and Lambris,J.D. (1996). Inhibition of human complement by a C3-binding peptide isolated from a phage-displayed random peptide library. Journal of Immunology, 157 (2):884-891 |
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| Stavridi,E.S., OMalley,K., Lukacs,C.M., Moore,W.T., Lambris,J.D., Christianson,D.W., Rubin,H. and Cooperman,B.S. (1996). Structural change in alpha-chymotrypsin induced by complexation with alpha(1)-antichymotrypsin as seen by enhanced sensitivity to proteolysis. Biochemistry, 35 (33):10608-10615 |
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| Sunyer,J.O., Zarkadis,I.K., Sahu,A. and Lambris,J.D. (1996). Multiple forms of complement C3 in trout that differ in binding to complement activators. Proceedings of the National Academy of Sciences of the United States of America, 93 (16):8546-8551 |
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| Kozlowski,L.M., Lambris,J.D. and Levinson,A.I. (1995). Effect of a putative B cell superantigen on complement. Immunoglobulin Gene Expression in Development and Disease, 764:356-358 |
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| Lambris,J.D., Pappas,J., Mavroidis,M., Wang,Y., Manzone,H., Schwager,J., Dupasquier,L. and Silibovsky,R. (1995). The 3Rd Component of Xenopus Complement - Cdna Cloning, Structural and Functional-Analysis, and Evidence for An Alternative C3 Transcript. European Journal of Immunology, 25 (5):572-578 |
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| Mavroidis,M., Sunyer,J.O. and Lambris,J.D. (1995). Isolation, Primary Structure, and Evolution of the 3Rd Component of Chicken Complement and Evidence for A New Member of the Alpha(2)-Macroglobulin Family. Journal of Immunology, 154 (5):2164-2174 |
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| Hasty,L.A., Lambris,J.D., Lessey,B.A., Pruksananonda,K. and Lyttle,C.R. (1994). Hormonal-Regulation of Complement Components and Receptors Throughout the Menstrual-Cycle. American Journal of Obstetrics and Gynecology, 170 (1):168-175 |
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| Hedrick,J.A., Lao,Z., Lipps,S.G., Wang,Y., Todd,S.C., Lambris,J.D. and Tsoukas,C.D. (1994). Characterization of A 70-Kda, Ebv Gp350/220-Binding Protein on Hsb-2 T-Cells. Journal of Immunology, 153 (10):4418-4426 |
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| Hung,S.L., Peng,C., Kostavasili,I., Friedman,H.M., Lambris,J.D., Eisenberg,R.J. and Cohen,G.H. (1994). The Interaction of Glycoprotein-C of Herpes-Simplex Virus Type-1 and Type-2 with the Alternative Complement Pathway. Virology, 203 (2):299-312 |
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| Lambris,J.D., Mavroidis,M., Pappas,J., Lao,Z.G. and Wang,Y. (1994). Phylogeny of the 3Rd Complement Component, C3, and Conservation of C3-Ligand Interactions. Primordial Immunity: Foundations for the Vertebrate Immune System, 712:354-357 |
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| Lao,Z.G., Wang,Y., Mavroidis,M., Kostavasili,I. and Lambris,J.D. (1994). Overexpression, Purification, and Characterization of 3Rd Component of Complement. Journal of Immunological Methods, 176 (1):127-139 |
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| Smith,C.I.E., Baskin,B., Humiregreiff,P., Zhou,J.N., Olsson,P.G., Maniar,H.S., Kjellen,P., Lambris,J.D., Christensson,B., Hammarstrom,L., Bentley,D., Vetrie,D., Islam,K.B., Vorechovsky,I. and Sideras,P. (1994). Expression of Brutons Agammaglobulinemia Tyrosine Kinase Gene, Btk, Is Selectively Down-Regulated in T-Lymphocytes and Plasma-Cells. Journal of Immunology, 152 (2):557-565 |
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| Hasty,L.A., Brockman,W.W., Lambris,J.D. and Lyttle,C.R. (1993). Hormonal-Regulation of Complement Factor-B in Human Endometrium. American Journal of Reproductive Immunology, 30 (2-3):63-67 |
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| Lambris,J.D., Lao,Z., Pang,J. and Alsenz,J. (1993). 3Rd Component of Trout Complement - Cdna Cloning and Conservation of Functional Sites. Journal of Immunology, 151 (11):6123-6134 |
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| Sinha,S.K., Todd,S.C., Hedrick,J.A., Speiser,C.L., Lambris,J.D. and Tsoukas,C.D. (1993). Characterization of the Ebv/C3D Receptor on the Human Jurkat T-Cell Line - Evidence for A Novel Transcript. Journal of Immunology, 150 (12):5311-5320 |
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| Alsenz,J., Avila,D., Huemer,H.P., Esparza,I., Becherer,J.D., Kinoshita,T., Wang,Y., Oppermann,S. and Lambris,J.D. (1992). Phylogeny of the 3Rd Component of Complement, C3 - Analysis of the Conservation of Human-Cr-1, Human-Cr-2, Human-H, and Human-B Sites, Concanavalin-A Binding-Sites, and Thiolester Bond in the C3 from Different Species. Developmental and Comparative Immunology, 16 (1):63-76 |
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| Becherer,J.D., Alsenz,J., Esparza,I., Hack,C.E. and Lambris,J.D. (1992). Segment Spanning Residues-727-768 of the Complement-C3 Sequence Contains A Neoantigenic Site and Accommodates the Binding of Cr-1, Factor-H, and Factor-B. Biochemistry, 31 (6):1787-1794 |
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| Hedrick,J.A., Watry,D., Speiser,C., Odonnell,P., Lambris,J.D. and Tsoukas,C.D. (1992). Interaction Between Epstein-Barr-Virus and A T-Cell Line (Hsb-2) Via A Receptor Phenotypically Distinct from Complement Receptor Type-2. European Journal of Immunology, 22 (5):1123-1131 |
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| Kaufman,J., Andersen,R., Avila,D., Engberg,J., Lambris,J., Salomonsen,J., Welinder,K. and Skjodt,K. (1992). Different Features of the Mhc Class-I Heterodimer Have Evolved at Different Rates - Chicken B-F and Beta-2-Microglobulin Sequences Reveal Invariant Surface Residues. Journal of Immunology, 148 (5):1532-1546 |
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| Nilsson,B., Grossberger,D., Ekdahl,K.N., Riegert,P., Becherer,D.J., Nilsson,U.R. and Lambris,J.D. (1992). Conformational Differences Between Surface-Bound and Fluid-Phase Complement-Component-C3 Fragments - Epitope Mapping by Cdna Expression. Biochemical Journal, 282:715-721 |
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| Esparza,I., Becherer,J.D., Alsenz,J., Delahera,A., Lao,Z., Tsoukas,C.D. and Lambris,J.D. (1991). Evidence for Multiple Sites of Interaction in C3 for Complement Receptor Type-2 (C3D/Ebv Receptor, Cd21). European Journal of Immunology, 21 (11):2829-2838 |
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| Moller,L.B., Kaufman,J., Verland,S., Salomonsen,J., Avila,D., Lambris,J.D. and Skjodt,K. (1991). Variations in the Cytoplasmic Region Account for the Heterogeneity of the Chicken Mhc Class-I (B-F) Molecules. Immunogenetics, 34 (2):110-120 |
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| Watry,D., Hedrick,J.A., Siervo,S., Rhodes,G., Lamberti,J.J., Lambris,J.D. and Tsoukas,C.D. (1991). Infection of Human Thymocytes by Epstein-Barr-Virus. Journal of Experimental Medicine, 173 (4):971-980 |
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| Avila,D. and Lambris,J.D. (1990). Isolation and Characterization of the 3Rd Complement Component of Axolotl (Ambystoma-Mexicanum). Comparative Biochemistry and Physiology B-Biochemistry & Molecular Biology, 95 (4):839-845 |
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| Nilsson,B., Ekdahl,K.N., Avila,D., Nilsson,U.R. and Lambris,J.D. (1990). Neoantigens in Complement Component-C3 As Detected by Monoclonal-Antibodies - Mapping of the Recognized Epitopes by Synthetic Peptides. Biochemical Journal, 268 (1):55-61 |
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| Tsokos,G.C., Lambris,J.D., Finkelman,F.D., Anastassiou,E.D. and June,C.H. (1990). Monovalent Ligands of Complement Receptor-2 Inhibit Whereas Polyvalent Ligands Enhance Anti-Ig-Induced Human-B Cell Intracytoplasmic Free Calcium-Concentration. Journal of Immunology, 144 (5):1640-1645 |
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| Alsenz,J., Lambris,J.D., Bork,K. and Loos,M. (1989). Acquired C1 Inhibitor (C1-Inh) Deficiency Type-Ii - Replacement Therapy with C1-Inh and Analysis of Patients C1-Inh and Anti-C1-Inh Autoantibodies. Journal of Clinical Investigation, 83 (6):1794-1799 |
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| Baxevanis,C.N., Reclos,G.J., Servis,C., Anastasopoulos,E., Arsenis,P., Katsiyiannis,A., Matikas,N., Lambris,J.D. and Papamichail,M. (1989). Peptides of Myelin Basic-Protein Stimulate Lymphocytes-T from Patients with Multiple-Sclerosis. Journal of Neuroimmunology, 22 (1):23-30 |
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| Bogen,B. and Lambris,J.D. (1989). Minimum Length of An Idiotypic Peptide and A Model for Its Binding to A Major Histocompatibility Complex Class-Ii Molecule. Embo Journal, 8 (7):1947-1952 |
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| Dihanich,M., Vantuinen,E., Lambris,J.D. and Marshallsay,B. (1989). Accumulation of Viruslike Particles in A Yeast Mutant Lacking A Mitochondrial Pore Protein. Molecular and Cellular Biology, 9 (3):1100-1108 |
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| Grossberger,D., Marcuz,A., Dupasquier,L. and Lambris,J.D. (1989). Conservation of Structural and Functional Domains in Complement Component C-3 of Xenopus and Mammals. Proceedings of the National Academy of Sciences of the United States of America, 86 (4):1323-1327 |
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| Huemer,H.P., Broker,M., Larcher,C., Lambris,J.D. and Dierich,M.P. (1989). The Central Segment of Herpes-Simplex Virus Type-1 Glycoprotein-C (Gc) Is Not Involved in C3B Binding - Demonstration by Using Monoclonal-Antibodies and Recombinant Gc Expressed in Escherichia-Coli. Journal of General Virology, 70:1571-1578 |
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| Lassila,O., Lambris,J.D. and Gisler,R.H. (1989). A Role for Lys-His-Gly-Nh2 in Avian and Murine B-Cell Development. Cellular Immunology, 122 (2):319-328 |
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| Pluschke,G., Bordmann,G., Daoudaki,M.E., Lambris,J.D., Achtman,M. and Neibert,M. (1989). Isolation of Rat Igm to Igg Hybridoma Isotype Switch Variants and Analysis of the Efficiency of Rat Ig in Complement Activation. European Journal of Immunology, 19 (1):131-135 |
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| Servis,C. and Lambris,J.D. (1989). C-3 Synthetic Peptides Support Growth of Human Cr2-Positive Lymphoblastoid B-Cells. Journal of Immunology, 142 (7):2207-2212 |
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| Becherer,J.D. and Lambris,J.D. (1988). Identification of the C3B Receptor-Binding Domain in 3Rd Component of Complement. Journal of Biological Chemistry, 263 (28):14586-14591 |
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| Daoudaki,M.E., Becherer,J.D. and Lambris,J.D. (1988). A 34-Amino Acid Peptide of the Third Component of Complement Mediates Properdin Binding. Journal of Immunology, 140 (5):1577-1580 |
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| Gisler,R.H., Schlienger,C., Soderberg,A., Ledermann,F. and Lambris,J.D. (1988). Functional Maturation of Murine-B Lymphocyte Precursors .3. Soluble Factors Involved in the Regulation of Growth and Differentiation. Molecular Immunology, 25 (11):1113-1127 |
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| Lambris,J.D., Avila,D., Becherer,J.D. and Mullereberhard,H.J. (1988). A Discontinuous Factor-H Binding-Site in the 3Rd Component of Complement As Delineated by Synthetic Peptides. Journal of Biological Chemistry, 263 (24):12147-12150 |
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| Reclos,J.G., Baxevanis,C.N., Servis,K., Arsenis,P., Katsiyiannis,A., Matikas,N., Lambris,J.D. and Papamichail,M. (1988). Proliferative responces of T lymphocytes from patients with Multiple Sclerosis to human myelin basic protein peptides. In Trends in European Multiple Sclerosis research. Elsevier Science Pub.,211-215 |
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| Tsoukas,C.D. and Lambris,J.D. (1988). Expression of Cr2/Ebv Receptors on Human Thymocytes Detected by Monoclonal-Antibodies. European Journal of Immunology, 18 (8):1299-1302 |
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| Frei,Y., Lambris,J.D. and Stockinger,B. (1987). Generation of A Monoclonal-Antibody to Mouse C5 Application in An Elisa Assay for Detection of Anti-C5 Antibodies. Molecular and Cellular Probes, 1 (2):141-149 |
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| Hirani,S., Lambris,J.D. and Mullereberhard,H.J. (1986). Structural-Analysis of the Asparagine-Linked Oligosaccharides of Human-Complement Component-C3. Biochemical Journal, 233 (2):613-616 |
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| Inghirami,G., Lambris,J.D. and Tsokos,G.C. (1986). Complement Receptors (Cr) and Cytotoxic Responses - Monoclonal-Antibodies Directed Against Cr-1 and Cr3 Inhibit the Generation of Human Allospecific and Virus Specific Cytotoxic Cells-Invitro. Journal of Immunopharmacology, 8 (1):75-88 |
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| Tsokos,G.C., Inghirami,G. and Lambris,J.D. (1986). Regulation of Human Cytotoxic Responses by Complement - C-3, C3B and C3D Preparations Enhance Human Allogeneic Cytotoxic Responses. Journal of Immunopharmacology, 8 (4):529-541 |
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| Tsonis,P.A. and Lambris,J.D. (1986). Similarities Between A Conserved Sequence Element of Homoeo Boxes and Other Genes. Febs Letters, 194 (2):263-266 |
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| Aguado,M.T., Lambris,J.D., Tsokos,G.C., Burger,R., Bittersuermann,D., Tamerius,J.D., Dixon,F.J. and Theofilopoulos,A.N. (1985). Monoclonal-Antibodies Against Complement-3 Neoantigens for Detection of Immune-Complexes and Complement Activation - Relationship Between Immune-Complex Levels, State of C-3, and Numbers of Receptors for C3B. Journal of Clinical Investigation, 76 (4):1418-1426 |
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| Alsenz,J., Schulz,T.F., Lambris,J.D., Sim,R.B. and Dierich,M.P. (1985). Structural and Functional-Analysis of the Complement Component Factor-H with the Use of Different Enzymes and Monoclonal-Antibodies to Factor-H. Biochemical Journal, 232 (3):841-850 |
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| Hirani,S., Lambris,J.D. and Mullereberhard,H.J. (1985). Localization of the Conglutinin Binding-Site on the 3Rd Component of Human-Complement. Journal of Immunology, 134 (2):1105-1109 |
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| Lambris,J.D., Hirani,S., Ganu,V.S., Becherer,D. and Müller-Eberhard,H.J. (1985). Synthetic peptides predicted from the nucleotide sequence of complement C3 bind to C3d receptor and monoclonal antibody 130. Advances in Gene Technology:Molecular Biology of the Immune System, 2:213-214 |
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| Pryzwansky,K.B., Lambris,J.D., Macrae,E.K. and Schwab,J.H. (1985). Opsonized Streptococcal Cell-Walls Cross-Link Human-Leukocytes and Erythrocytes by Complement Receptors. Infection and Immunity, 49 (3):550-556 |
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| Schulz,T.F., Scharfenberger,H., Lambris,J.D., Rieber,P., Riethmuller,G. and Dierich,M.P. (1985). Antigenic Relationship Between the Alpha-Chain of C-3, A Leucocyte-Surface Antigen Involved in the Activation of Phagocytic-Cells, and A 50,000 Mw B-Cell Antigen. Immunology, 54 (4):791-800 |
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| Tsokos,G.C., Inghirami,G., Tsoukas,C.D., Balow,J.E. and Lambris,J.D. (1985). Regulation of Immunoglobulin Secretion by Factor-H of Human-Complement. Immunology, 55 (3):419-426 |
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| Alsenz,J., Lambris,J.D., Schulz,T.F. and Dierich,M.P. (1984). Localization of the Complement-Component-C3B-Binding Site and the Cofactor Activity for Factor-I in the 38Kda Tryptic Fragment of Factor-H. Biochemical Journal, 224 (2):389-398 |
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| Lambris,J.D. and Mullereberhard,H.J. (1984). Isolation and Characterization of A 33,000-Dalton Fragment of Complement Factor-B with Catalytic and C3B Binding-Activity. Journal of Biological Chemistry, 259 (20):2685-2690 |
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| Lambris,J.D., Alsenz,J., Schulz,T.F. and Dierich,M.P. (1984). Mapping of the Properdin-Binding Site in the 3Rd Component of Complement. Biochemical Journal, 217 (1):323-326 |
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| Schulz,T.F., Scheiner,O., Alsenz,J., Lambris,J.D. and Dierich,M.P. (1984). Use of Monoclonal-Antibodies Against Factor-H to Investigate the Role of A Membrane-Associated Protein Antigenically Related to H in C3B-Receptor Function. Journal of Immunology, 132 (1):392-398 |
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| Tsoukas,C.D., Lambris,J., Lotz,M., Valentine,M.A., Vaughan,J.H. and Carson,D.A. (1984). Lymphocyte Mitogenesis Induced by Monoclonal-Antibodies to the T3-Complex - Differential Modulation by Human-Igg. Cellular Immunology, 89 (1):66-74 |
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| Huttfletcher,L.M., Fowler,E., Lambris,J.D., Feighny,R.J., Simmons,J.G. and Ross,G.D. (1983). Studies of the Epstein-Barr Virus Receptor Found on Raji Cells .2. A Comparison of Lymphocyte Binding-Sites for Epstein-Barr Virus and C3D. Journal of Immunology, 130 (3):1309-1312 |
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| Lambris,J.D., Scheiner,O., Schulz,T.F., Alsenz,J. and Dierich,M.P. (1983). Coupling of C3B to Erythrocytes by Disulfide Bond Formation - Preparation of Ec3B for Hemolytic and Complement Receptor Assays. Journal of Immunological Methods, 65 (3):277-283 |
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| Pryzwansky,K.B., Macrae,E.K. and Lambris,J.D. (1983). Capping of Complement Receptors on Human-Neutrophils Induced by Group-A Streptococcal Cell-Walls. Journal of Immunology, 130 (4):1674-1677 |
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| Ross,G.D., Newman,S.L., Lambris,J.D., Deverypocius,J.E., Cain,J.A. and Lachmann,P.J. (1983). Generation of 3 Different Fragments of Bound C-3 with Purified Factor-I Or Serum .2. Location of Binding-Sites in the C-3 Fragments for Factor-B and Factor-H Complement Receptors, and Bovine Conglutinin. Journal of Experimental Medicine, 158 (2):334-352 |
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| Scheiner,O., Schulz,T.F., Schmid,H.U., Lambris,J.D., Alsenz,J. and Dierich,M.P. (1983). Importance of Factor-H and Factor-I for the Adherence of C3B-Coated Erythrocytes to Cells. Immunobiology, 165 (2):211-224 |
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| Lambris,J., Papamichail,M., Ioannidis,C. and Dimitracopoulos,G. (1982). Activation of the Alternative Pathway of Human-Complement by the Extracellular Slime Glycolipoprotein of Pseudomonas-Aeruginosa. Journal of Infectious Diseases, 145 (1):78-82 |
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| Lambris,J.D. and Ross,G.D. (1982). Assay of Membrane Complement Receptors (Cr-1 and Cr-2) with C3B-Coated and C3D-Coated Fluorescent Microspheres. Journal of Immunology, 128 (1):186-189 |
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| Lambris,J.D., Allen,J.B. and Schwab,J.H. (1982). Invivo Changes in Complement Induced with Peptidoglycan-Polysaccharide Polymers from Streptococcal Cell-Walls. Infection and Immunity, 35 (1):377-380 |
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| Lambris,J.D. and Ross,G.D. (1982). Characterization of the Lymphocyte Membrane-Receptor for Factor-H (Beta-1H-Globulin) with An Antibody to Anti-Factor-H Idiotype. Journal of Experimental Medicine, 155 (5):1400-1411 |
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| Ross,G.D., Lambris,J.D., Cain,J.A. and Newman,S.L. (1982). Generation of 3 Different Fragments of Bound-C3 with Purified Factor-I Or Serum .1. Requirements for Factor-H Vs Cr-1 Cofactor Activity. Journal of Immunology, 129 (5):2051-2060 |
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| Ross,G.D. and Lambris,J.D. (1982). Identification of A C3Bi-Specific Membrane Complement Receptor That Is Expressed on Lymphocytes, Monocytes, Neutrophils, and Erythrocytes. Journal of Experimental Medicine, 155 (1):96-110 |
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| Tsiganos,C.P., Stamatiadou,M., Lambris,J.D. and Papamichail,M. (1982). Detection of cartilage proteoglycan-related antigens on the surface of 3T3 cells. Progress in Clinical & Biological Research, 102 pt A:447-454 |
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| Dobson,N.J., Lambris,J.D. and Ross,G.D. (1981). Characteristics of Isolated Erythrocyte Complement Receptor Type One (Cr-1, C4B-C3B Receptor) and Cr1-Specific Antibodies. Journal of Immunology, 126 (2):693-698 |
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| Lambris,J. and Papamichail,M. (1980). A Method for Analyzing Lymphocyte Surface-Antigens. Journal of Immunological Methods, 34 (4):287-293 |
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| Lambris,J., Papavassiliou,J. and Dimitracopoulos,G. (1980). Protein-Component of Pseudomonas-Aeruginosa Slime Glycolipoprotein in Relation to Laboratory-Induced Resistance to Gentamicin. Canadian Journal of Microbiology, 26 (7):852-853 |
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| Lambris,J.D., Dobson,N.J. and Ross,G.D. (1980). Release of Endogenous C3B Inactivator from Lymphocytes in Response to Triggering Membrane-Receptors for Beta-1H Globulin. Journal of Experimental Medicine, 152 (6):1625-1644 |
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| Lambris,J., Papamichail,M. and Fessas,P. (1979). Fluorescent Labeling of Proteins of Lymphocyte Plasma-Membranes. Journal of Immunological Methods, 27 (1):55-59 |
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