Present Support
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2007-2012 |
Complement in cell proliferation and injury - therapeutic interventions. NIH effort 40%. Total Support $7,500,000. (Priority Score 154). |
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2007-2011 |
Design of novel complement inhibitors. NIH Total Support $1,260,000. (Priority Score 127, 7.7 Percentile). |
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2007-2012 |
Thermodynamic and structural studies on formation of the C3 convertase. NIH effort 10%. Total Support $1,981,250. (2.9 Percentile). |
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2007-2012 |
Complement mediated neuronal injury in stroke. NIH (P.I.Connely, Columbia University), effort 5%. Total Support for JDL $634,000. |
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2007-2012 |
Structural functional analysis of staphylococcal complement inhibitors. NIH (P.I.Geisbrecht, B University of Missouri-Kansas City), Total Support for JDL $780,000. (9.9 Percentile). |
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2006 |
Structural and functional analysis of C3. NIH AI 30040 Total Support $1,631,875. (2 Percentile). |
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2005-2010 |
The role of complement in ovarian cancer. NIH Total Support $1,585.000. (3.6 Percentile). |
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2005-2010 |
Biomaterial-induced complement activation. NIH Total Support $1,064,213. (12.7 Percentile). |
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2004-2008 |
Computer aided design of complement therapeutics. NIH R24GM069736 Total Support $1,871,000. (Priority Score 127, 7.7 Percentile). |
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Past Grants
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2004-2007 |
In Silico De Novo protein design: A Dynamically Data Driven, (DDDAS), Computational and experimental framework . ITR:Collaborative Research: (ASE+NHS+EVS)-(sim+dmc+int) NSF 0426691 (P.I.Floudas, C. Princeton), effort 10%. Total Support for JDL $370,000. |
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2003-2007 |
Defence against biowarfare and emerging infection agents. Sub project 3 of poxvirus project: Indentify the targets of VIG using proteomics approach. NIH U54 AI057168-01 effort 10%. Total Support $720,000. |
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2002-2007 |
The role of complement in liver regeneration. NIH Total Support $1,270,000. |
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2002-2006 |
Virus and immune injury to vessels wall cells. NIH HL28220 (P.I.Friedman, H), effort 5%. Total Support for JDL $200,000. |
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2001-2007 |
Structural-functional analysis of Compstatin. NIH GM-62134 Total Support $1,300,000. (9.9 Percentile). |
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2001-2006 |
Vaccinia B5R protein in spread immune evasion, vaccines. NIH (P.I.Isaacs, S), effort 5%. Total Support for JDL $395,500. |
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2000-2006 |
Structural and functional analysis of C3. NIH AI 30040 Total Support $1,193,000. |
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2000-2004 |
Poxvirus SCR-containing proteins as therapeutic targets. NIH (P.I.Isaacs, S), effort 5%. Total Support for JDL $521,500. |
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1999 |
Purchase of a MALDI/MS system. NIH Total Support $250,000. |
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1998-2003 |
Studies on complement diversity and evolution. NIH GM-56698 effort %10. Total Support $1,231,877. |
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1998-2003 |
Role of B cells in autoimmune diabetes. NIH (P.I.Naji, A), effort 5%. Total Support for JDL $324,320. |
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1997 |
Purchase of an HPLC system. Research Foundation of the University of Pennsylvania Total Support $14,500. |
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1997-2002 |
Early events in Herpes Simplex Virus Entry. NIH (P.I.Eisenberg, R), effort 5%. Total Support for JDL $159,000. |
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1997-2003 |
Pathogenesis of persistent viral injury to the CNS-Sub: Early events in herpes simple virus entry into cells of neural origin. NIH (P.I.Eisenberg, R), effort 5%. Total Support for JDL $160,000. |
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1997-2002 |
Cellular interactions of plasma proteins. NIH P-10-HL-56914 (P.I.Walsh, P), effort 10%. Total Support for JDL $688,000. |
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1996-2001 |
Virus and immune injury to vessel wall cells. NIH 5 RO1 HL28220 effort 10%. Total Support $625,770. |
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1995 |
Purchase of multiple peptide synthesizer. Research Foundation of the University of Pennsylvania Total Support $32,000. |
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1995-1999 |
CSVTCG-Specific thrombospondin receptor in breast cancer. NIH CA65675 (P.I.Tuszynski, G), effort 10%. Total Support for JDL $379,624. |
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1994-1997 |
Structural and functional analysis of complement proteins from different species. NSF MCB-9319111 Total Support $300,000. |
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1993-1998 |
Structural and functional analysis of C3 from different species. NIH AI 30040 Total Support $1,124,199. |
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1992-1995 |
Peritoneal macrophage migration in endometriosis. NIH HD 30475 (P.I.Coutifaris, C), effort 10%. Total Support for JDL $297,241. |
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1991-1992 |
Research Grant. Research Foundation of the University of Pennsylvania URF-3-71696 Total Support $12,000. |
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1991-1994 |
Structural and functional analysis of chicken and lamprey C3. NSF DCB-9018751 Total Support $300,000. |
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1991-2002 |
Support Grant. University of Pennsylvania Diabetes Center 2P30-DK-19525 (P.I.Matschinsky, F), effort 10%. Total Support for JDL $480,625. |
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1990-1991 |
Structural analysis of C3d/EBV-CR2 interactions. American Cancer Society IN-135K Total Support 10,000. |
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1989-2001 |
Support Grant. University of Pennsylvania Cancer Center 5P30-CA-16520 (P.I.Glick, J), effort 10%. Total Support for JDL $710,000. |
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1984-1987 |
Research Grant. NIH 1R01-AI21014 Total Support $320,000. |
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1982-1984 |
Research Grant. American Cancer Society IM-308 Total Support $140,000. |
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1982-1984 |
New Investigator Award. NIH IR23-AI-18546 Total Support $180,000. |
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