Grants Received

2014-2019Complement in inflammatory diseases: Mechanisms & therapeutic modulation
NIH P01-AI068730
Total Support $10,000,000
(Priority Score 1)
2013-2017Disarming the intravascular innate immune response to improve modalities for chronic kidney disease treatment
DIREKT (FP7-HEALTH-2013-INNOVATION-1)
EUROPEAN GRANT
PI: B Nilsson; Co-PI: JD Lambris
Total Support for JD Lambris: $1,000,000
2013-2017Structural analysis of the third component of complement
NIH AI 30040
Total Support $1,471,833
2012-2016Novel mechanisms and Complement-ary therapy in periodontitis
NIH DE021685
PI: G Hajishengallis; Co-PI: JD Lambris
Total Support: $2,000,000
2012-2015A novel approach for assessing dynamic events in the human complement system
NIH R21-AI097805
PI: D. Ricklin; Co-PI: John D. Lambris
Total Support: $676,800
2011-2016Complement inhibition as sepsis therapy
NIH 1-R01-GM-097747-01
M.P.I. JD Lambris & F Lupu (University of Oklahoma)
Total Support $2,084,220
2011-2015Complement in AMD: Mechanisms and therapeutic intervention
NIH 5-R01-EY-020633
2012-2013Complement based therapies to periodontal disease
ITMAT University of Pennsylvania
UL1RR024134
2011-2012A novel iron-amyloid beta pathway for complement activation quantified with a new high sensitivity assay
Beckman Foundation (Arnold and Mabel)
(P.I. Dunaief, Joshua L University of Pennsylvania)
2007-2012Complement in cell proliferation and injury - therapeutic interventions
NIH, effort 40%
Total Support $7,500,000
(Priority Score 154)
2007-2012Complement mediated neuronal injury in stroke
NIH (P.I.Connely, Columbia University), effort 5%
Total Support for JDL $634,000.
2007-2012Design of novel complement inhibitors
NIH
Total Support $1,260,000
(Priority Score 127, 7.7 Percentile)
2007-2012Structural functional analysis of staphylococcal complement inhibitors
NIH
(P.I.Geisbrecht, B University of Missouri-Kansas City)
Total Support for JDL $780,000
(9.9 Percentile)
2007-2012Thermodynamic and structural studies on formation of the C3 convertase
NIH, effort 10%
Total Support $1,981,250
(2.9 Percentile)
2006-2012Structural and functional analysis of C3
NIH AI 30040
Total Support $1,631,875
(2 Percentile)
2005-2010Biomaterial-induced complement activation
NIH
Total Support $1,064,213
(12.7 Percentile)
2005-2010The role of complement in ovarian cancer
NIH
Total Support $1,585,000
(3.6 Percentile)
2004-2008Computer aided design of complement therapeutics
NIH R24GM069736
Total Support $1,871,000
(Priority Score 127, 7.7 Percentile)
2004-2007In Silico De Novo protein design: A Dynamically Data Driven, (DDDAS), Computational and experimental framework
ITR: Collaborative Research: (ASE+NHS+EVS)-(sim+dmc+int) NSF 0426691
(P.I.Floudas, C. Princeton), effort 10%
Total Support for JDL $370,000.
2003-2007Defence against biowarfare and emerging infection agents. Sub project 3 of poxvirus project: Identify the targets of VIG using proteomics approach
NIH U54 AI057168-01, effort 10%
Total Support $720,000
2001-2007Structural-functional analysis of Compstatin
NIH GM-62134
Total Support $1,300,000
(9.9 Percentile)
2001-2006Vaccinia B5R protein in spread immune evasion, vaccines
NIH
(P.I.Isaacs, S), effort 5%
Total Support for JDL $395,500
2000-2006Structural and functional analysis of C3
NIH AI 30040
Total Support $1,193,000
2000-2004Poxvirus SCR-containing proteins as therapeutic targets
NIH
(P.I.Isaacs, S), effort 5%
Total Support for JDL $521,500
1999Purchase of a MALDI/MS system
NIH
Total Support $250,000
1998-2003Role of B cells in autoimmune diabetes
NIH
(P.I.Naji, A), effort 5%
Total Support for JDL $324,320
1998-2003Studies on complement diversity and evolution
NIH GM-56698, effort 10%
Total Support $1,231,877
1997-2003Pathogenesis of persistent viral injury to the CNS-Sub: Early events in herpes simple virus entry into cells of neural origin
NIH
(P.I.Eisenberg, R), effort 5%
Total Support for JDL $160,000
1997-2002Cellular interactions of plasma proteins
NIH P-10-HL-56914
(P.I.Walsh, P), effort 10%
Total Support for JDL $688,000
1997-2002Early events in Herpes Simplex Virus Entry
NIH
(P.I.Eisenberg, R), effort 5%
Total Support for JDL $159,000
1997Purchase of an HPLC system
Research Foundation of the University of Pennsylvania
Total Support $14,500
1996-2001Virus and immune injury to vessel wall cells
NIH 5 RO1 HL28220, effort 10%
Total Support $625,770
1995-1999CSVTCG-Specific thrombospondin receptor in breast cancer
NIH CA65675
(P.I.Tuszynski, G), effort 10%
Total Support for JDL $379,624
1995Purchase of multiple peptide synthesizer
Research Foundation of the University of Pennsylvania
Total Support $32,000
1994-1997Structural and functional analysis of complement proteins from different species
NSF MCB-9319111
Total Support $300,000
1993-1998Structural and functional analysis of C3 from different species
NIH AI 30040
Total Support $1,124,199
1992-1995Peritoneal macrophage migration in endometriosis
NIH HD 30475
(P.I.Coutifaris, C), effort 10%
Total Support for JDL $297,241
1991-2002Support Grant
University of Pennsylvania Diabetes Center
2P30-DK-19525
(P.I.Matschinsky, F), effort 10%
Total Support for JDL $480,625
1991-1994Structural and functional analysis of chicken and lamprey C3
NSF DCB-9018751
Total Support $300,000
1991-1992Research Grant
Research Foundation of the University of Pennsylvania
URF-3-71696
Total Support $12,000
1990-1991Structural analysis of C3d/EBV-CR2 interactions
American Cancer Society
IN-135K
Total Support $10,000
1989-2001Support Grant
University of Pennsylvania Cancer Center
5P30-CA-16520 (P.I.Glick, J), effort 10%
Total Support for JDL $710,000
1984-1987Research Grant
NIH 1R01-AI21014
Total Support $320,000
1982-1984New Investigator Award
NIH IR23-AI-18546
Total Support $180,000
1982Research Grant
American Cancer Society IM-308
Total Support $140,000