Reviews & Chapters

Lamers C, Ricklin D, Lambris JD. (2023). Complement-Targeted Therapeutics: An Emerging Field Enabled by Academic Drug Discovery. Am J Hematol. [Online ahead of print].
Mannes M, Mastellos DC, Ekdahl KN, Nilsson B, Yancopoulou D, Lambris JD, Huber-Lang M. (2022). Complement C3 activation in the ICU: Disease and therapy as Bonnie and Clyde. Semin. Immunol. 60:101640.
Mastellos DC, Lambris JD. (2022). Recent developments in C3-targeted complement therapeutics. Semin. Immunol. 60:101645.
Diamond MS, Lambris JD, Ting JP, Tsang JS. (2022). Considering innate immune responses in SARS-CoV-2 infection and COVID-19. Nat Rev Immunol. 22:465-470.
Kim BJ, Liu T, Mastellos DC, Lambris JD. (2022). Emerging opportunities for C3 inhibition in the eye. Semin. Immunol. 59:101633.
Geisbrecht BV, Lambris JD, Gros P. (2022). Complement component C3: A structural perspective and potential therapeutic implications. Semin. Immunol. 59:101627
Kajikawa T, Mastellos DC, Hasturk H, Kotsakis GA, Yancopoulou D, Lambris JD, Hajishengallis G. (2022). C3-targeted host-modulation approaches to oral inflammatory conditions. Semin. Immunol. 59:101608.
Mollnes TE, Storm BS, Brekke OL, Nilsson PH, Lambris JD. (2022). Application of the C3 inhibitor compstatin in a human whole blood model designed for complement research - 20 years of experience and future perspectives. Semin. Immunol. 59:101604.
Lamers C, Mastellos DC, Ricklin D, Lambris JD. (2022). Compstatins: the dawn of clinical C3-targeted complement inhibition. Trends in Pharmacological Sciences 43: 629-640. Trends Talk.
Hajishengallis G, Hasturk H, Lambris JD, Contributing authors. (2021). C3-targeted therapy in periodontal disease: moving closer to the clinic. Trends in Immunology. 42: 856-864.
Mastellos DC, Skendros P, Lambris JD. (2021). Is complement the culprit behind COVID-19 vaccine-related adverse reactions? J. Clin. Invest. 131: 151092.
Mastellos DC, Skendros P, Calado RT, Risitano AM, Lambris JD. (2021). Efficacy matters: broadening complement inhibition in COVID-19. The Lancet Rheumatology 3: e95.
Kim BJ, Mastellos DC, Li Y, Dunaief JL, Lambris JD. (2020). Targeting complement components C3 and C5 for the retina: Key concepts and lingering questions. Prog Retin Eye Res. 13: 100936.
Hajishengallis G, Chavakis T, Lambris JD. (2020). Current understanding of periodontal disease pathogenesis and targets for host‐modulation therapy. Periodontol 2000 84: 14– 34.
Hajishengallis G, Kajikawa T, Hajishengallis E, Maekawa T, Li X, Belibasakis GN, Bostanci N, Mastellos DC, Yancopoulou D, Hasturk H, and Lambris JD. (2020). Complement C3 as a Target of Host Modulation in Periodontitis. Emerging Therapies in Periodontics pp: 13-29.
Risitano AM, Mastellos DC, Huber-Lang M, Yancopoulou D, Garlanda C, Ciceri F, Lambris JD. (2020). Comment: Complement as a target in COVID-19? Nature Reviews Immunology 20: 343-344.
Mastellos DC, Reis ES, Lambris JD. (2020). Editorial: Therapeutic Modulation of the Complement System: Clinical Indications and Emerging Drug Leads. Frontiers in Immunology 10: 3029.
Hajishengallis G, Kajikawa T, Hajishengallis E, Maekawa T, Reis ES, Mastellos DC, Yancopoulou D, Hasturk H, Lambris JD. (2019). Complement-Dependent Mechanisms and Interventions in Periodontal Disease. Frontiers in Immunology 10: 406.
Karasu E, Nilsson B, Kohl J, Lambris JD, Huber-Lang M. (2019). Targeting Complement Pathways in Polytrauma- and Sepsis-Induced Multiple-Organ Dysfunction. Frontiers in Immunology 10: 543.
Mastellos DC, Blom AM, Connolly ES, Daha MR, Geisbrecht BV, Ghebrehiwet B, Gros P, Hajishengallis G, Holers VM, Huber-Lang M, Kinoshita T, Mollnes TE, Montgomery RA, Morgan BP, Nilsson B, Pio R, Ricklin D, Risitano AM, Taylor RP, Mantovani A, Ioannidis JP, Lambris JD. (2019). 'Stealth' corporate innovation: an emerging threat for therapeutic drug development. Nature immunology 20: 1409-1413.
Mastellos DC, Ricklin D, Lambris JD. (2019). Clinical promise of next-generation complement therapeutics. Nature Reviews. Drug Discovery 18: 707-729. Additional Links: Poster.
Park DH, Connor KM, Lambris JD. (2019). The Challenges and Promise of Complement Therapeutics for Ocular Diseases. Frontiers in Immunology 10: 1007.
Pio R, Ajona D, Ortiz-Espinosa S, Mantovani A, Lambris JD. (2019). Complementing the Cancer-Immunity Cycle. Frontiers in Immunology 10: 774.
Reis ES, Mastellos DC, Hajishengallis G, Lambris JD. (2019). New insights into the immune functions of complement. Nature Reviews. Immunology 19: 503-516.
Smith RJ, Appel GB, Blom AM, Cook HT, D'Agati VD, Fakhouri F, Fremeaux-Bacchi V, Jzsi M, Kavanagh D, Lambris JD, Noris M, Pickering MC, Remuzzi G, de Crdoba SR, Sethi S, Van der Vlag J, Zipfel PF, Nester CM. (2019). C3 glomerulopathy - understanding a rare complement-driven renal disease. Nature Reviews. Nephrology 15: 129-143.
Huber-Lang M, Lambris JD, Ward PA. (2018). Innate immune responses to trauma. Nature Immunology 19: 327-341.
Mastellos DC, Reis ES, Biglarnia AR, Waldman M, Quigg RJ, Huber-Lang M, Seelen MA, Daha MR, Lambris JD. (2018). Taming hemodialysis-induced inflammation: Are complement C3 inhibitors a viable option? Clinical Immunology 198: 102-105.
Mastellos DC, Reis ES, Lambris JD. (2018). Complement C5a-Mediated TAM-ing of Antitumor Immunity Drives Squamous Carcinogenesis. Cancer Cell 34: 531-533.
Mastellos DC, Reis ES, Yancopoulou D, Risitano AM, Lambris JD. (2018). Expanding Complement Therapeutics for the Treatment of Paroxysmal Nocturnal Hemoglobinuria. Seminars in Hematology 55: 167-175.
Ricklin D, Mastellos DC, Reis ES, Lambris JD. (2018). The renaissance of complement therapeutics. Nature Reviews. Nephrology 14: 26-47.
Hajishengallis G, Reis ES, Mastellos DC, Ricklin D, Lambris JD. (2017). Novel mechanisms and functions of complement. Nature Immunology 18: 1288-1298.
Mastellos DC, Reis ES, Ricklin D, Smith RJ, Lambris JD. (2017). Complement C3-Targeted Therapy: Replacing Long-Held Assertions with Evidence-Based Discovery. Trends in Immunology 38: 383-394.
Olsen I, Lambris JD, Hajishengallis G. (2017). Porphyromonas gingivalis disturbs host-commensal homeostasis by changing complement function. Journal of Oral Microbiology 9: 1340085.
Reis ES, Mastellos DC, Ricklin D, Mantovani A, Lambris JD. (2017). Complement in cancer: untangling an intricate relationship. Nature Reviews. Immunology 18: 5-18.
Hajishengallis G, Hajishengallis E, Kajikawa T, Wang B, Yancopoulou D, Ricklin D, Lambris JD. (2016). Complement inhibition in pre-clinical models of periodontitis and prospects for clinical application. Seminars in Immunology 28: 285-291.
Hajishengallis G, Lambris JD. (2016). More than complementing Tolls: complement-Toll-like receptor synergy and crosstalk in innate immunity and inflammation. Immunological Reviews 274: 233-244.
Mastellos DC, Reis ES, Yancopoulou D, Hajishengallis G, Ricklin D, Lambris JD. (2016). From orphan drugs to adopted therapies: Advancing C3-targeted intervention to the clinical stage.Immunobiology 221: 1046-57.
Mastellos DC, Ricklin D, Hajishengallis E, Hajishengallis G, Lambris JD. (2016). Complement therapeutics in inflammatory diseases: promising drug candidates for C3-targeted intervention. Molecular Oral Microbiology 31: 3-17.
Ricklin D, Lambris JD. (2016). Complement therapeutics. Seminars in Immunology 28: 205-7.
Ricklin D, Lambris JD. (2016). Therapeutic control of complement activation at the level of the central component C3. Immunobiology 221: 740-6.
Ricklin D, Lambris JD. (2016). New milestones ahead in complement-targeted therapy. Seminars in Immunology 28: 208-22.
Ricklin D, Lambris JD. (2016). Preformed mediators of defense-Gatekeepers enter the spotlight Immunological Reviews 274: 5-8.
Ricklin D, Reis ES, Lambris JD. (2016). Complement in disease: a defence system turning offensive. Nature Reviews. Nephrology 12: 383-401.
Ricklin D, Reis ES, Mastellos DC, Gros P, Lambris JD. (2016). Complement component C3 - The "Swiss Army Knife" of Innate Immunity and host defense. Immunological Reviews 274: 33-58.
Schmidt CQ, Lambris JD, Ricklin D. (2016). Protection of host cells by complement regulators. Immunological Reviews 274: 152-171.
Hajishengallis G, Chavakis T, Hajishengallis E, Lambris JD. (2015). Neutrophil homeostasis and inflammation: novel paradigms from studying periodontitis. Journal of Leukocyte Biology 98: 539-48.
Hajishengallis G, Maekawa T, Abe T, Hajishengallis E, Lambris JD. (2015). Complement Involvement in Periodontitis: Molecular Mechanisms and Rational Therapeutic Approaches. Advances in Experimental Medicine and Biology 865: 57-74.
Kollias G, Lambris JD. (2015). A 'rule of 3' to revive Greek science, research and innovation. Nature Immunology 16: 1206-8.
Kourtzelis I, Magnusson PU, Kotlabova K, Lambris JD, Chavakis T. (2015). Regulation of Instant Blood Mediated Inflammatory Reaction (IBMIR) in Pancreatic Islet Xeno-Transplantation: Points for Therapeutic Interventions. Advances in Experimental Medicine and Biology 865: 171-88.
Mastellos DC, Yancopoulou D, Kokkinos P, Huber-Lang M, Hajishengallis G, Biglarnia AR, Lupu F, Nilsson B, Risitano AM, Ricklin D, Lambris JD. (2015). Compstatin: a C3-targeted complement inhibitor reaching its prime for bedside intervention. European Journal of Clinical Investigation 45: 423-40.
Reis ES, Mastellos DC, Yancopoulou D, Risitano AM, Ricklin D, Lambris JD. (2015). Applying complement therapeutics to rare diseases. Clinical Immunology (Orlando, Fla.) 161: 225-240.
Lupu F, Keshari RS, Lambris JD, Coggeshall KM. (2014). Crosstalk between the coagulation and complement systems in sepsis. Thrombosis Research 133 Suppl 1: S28-31.
Mastellos DC, Deangelis RA, Lambris JD. (2014). Inducing and characterizing liver regeneration in mice: Reliable models, essential. Current Protocols in Mouse Biology 3: 141-170.
Mastellos DC, Ricklin D, Yancopoulou D, Risitano A, Lambris JD. (2014). Complement in paroxysmal nocturnal hemoglobinuria: exploiting our current knowledge to improve the treatment landscape. Expert Review of Hematology 7: 583-98.
Hajishengallis G, Abe T, Maekawa T, Hajishengallis E, Lambris JD. (2013). Role of complement in host-microbe homeostasis of the periodontium. Seminars in Immunology 25: 65-72.
Hajishengallis G, Mantovani A, Moretta A, Lambris JD. (2013). Aegean reflections on innate immunity. Nature Immunology 14: 1025-9.
Lambris JD. (2013). Complement: More than killing. Seminars in Immunology 25: 1.
Mastellos DC, Deangelis RA, Lambris JD. (2013). Complement-triggered pathways orchestrate regenerative responses throughout phylogenesis. Seminars in Immunology 25: 29-38.
Phieler J, Garcia-Martin R, Lambris JD, Chavakis T. (2013). The role of the complement system in metabolic organs and metabolic diseases. Seminars in Immunology 25: 47-53.
Pio R, Ajona D, Lambris JD. (2013). Complement inhibition in cancer therapy. Seminars in Immunology 25: 54-64.
Pio R, Corrales L, Lambris JD. (2013). The role of complement in tumor growth. Advances in Experimental Medicine and Biology 772: 229-62.
Ricklin D, Lambris JD. (2013). Complement in immune and inflammatory disorders: pathophysiological mechanisms. Journal of Immunology 190: 3831-8.
Ricklin D, Lambris JD. (2013). Complement in immune and inflammatory disorders: therapeutic interventions. Journal of Immunology 190: 3839-47.
Brekke OL, Waage C, Christiansen D, Fure H, Qu H, Lambris JD, Osterud B, Nielsen EW, Mollnes TE. (2012). The Effects of Selective Complement and CD14 Inhibition on the E. coli-Induced Tissue Factor mRNA Upregulation, Monocyte Tissue Factor Expression, and Tissue Factor Functional Activity in Human Whole Blood. Advances in Experimental Medicine and Biology 734: 123-36.
Deangelis RA, Reis ES, Ricklin D, Lambris JD. (2012). Targeted complement inhibition as a promising strategy for preventing inflammatory complications in hemodialysis. Immunobiology 217: 1097-105.
Hajishengallis G, Lambris JD. (2012). Complement and dysbiosis in periodontal disease. Immunobiology 217: 1111-6.
Hajishengallis G, Lambris JD. (2012). Complement-targeted therapeutics in periodontitis. Advances in Experimental Medicine and Biology 734: 197-206.
Oikonomopoulou K, Reis ES, Lambris JD. (2012). Complement system and its role in immune responses. eLS 15-Aug-12.
Ricklin D, Lambris JD. (2012). Progress and trends in complement therapeutics. Advances in Experimental Medicine and Biology 734: 1-22.
Ricklin D, Reis ES, Lambris JD. (2012). A sweet spot to control complement-induced inflammation. Nature Medicine 18: 1340-1.
Schoengraf P, Lambris JD, Recknagel S, Kreja L, Liedert A, Brenner RE, Huber-Lang M, Ignatius A. (2012). Does complement play a role in bone development and regeneration? Immunobiology 218: 1-9.
Christiansen D, Brekke OL, Stenvik J, Lambris JD, Espevik T, Mollnes TE. (2011). Differential Effect of Inhibiting MD-2 and CD14 on LPS- Versus Whole E. coli Bacteria-Induced Cytokine Responses in Human Blood. Advances in Experimental Medicine and Biology 946: 237-51.
Ekdahl KN, Lambris JD, Elwing H, Ricklin D, Nilsson PH, Teramura Y, Nicholls IA, Nilsson B. (2011). Innate immunity activation on biomaterial surfaces: A mechanistic model and coping strategies. Advanced Drug Delivery Reviews 63: 1042-50.
Garcia BL, Ramyar KX, Ricklin D, Lambris JD, Geisbrecht BV. (2011). Advances in Understanding the Structure, Function, and Mechanism of the SCIN and Efb Families of Staphylococcal Immune Evasion Proteins. Advances in Experimental Medicine and Biology 946: 113-33.
Hajishengallis G, Krauss JL, Liang S, McIntosh ML, Lambris JD. (2011). Pathogenic microbes and community service through manipulation of innate immunity. Advances in Experimental Medicine and Biology 946: 69-85.
Hajishengallis G, Lambris JD. (2011). Microbial manipulation of receptor crosstalk in innate immunity. Nature Reviews Immunology 11: 187-200. Additional Links: At a glance, Supplementary info.
Oikonomopoulou K, Ricklin D, Ward PA, Lambris JD. (2011). Interactions between coagulation and complement-their role in inflammation. Seminars in immunopathology 34: 151-65.
Chi ZL, Yoshida T, Lambris JD, Iwata T. (2010). Suppression of Drusen Formation by Compstatin, a Peptide Inhibitor of Complement C3 activation, on Cynomolgus Monkey with Early-Onset Macular Degeneration. Advances in Experimental Medicine and Biology 703: 127-35.
Hajishengallis G, Lambris JD. (2010). Crosstalk pathways between Toll-like receptors and the complement system. Trends in Immunology 31: 154-63.
Hajishengallis G, Lambris JD. (2010). Illuminating the latest advances in innate immunity on the island of the sun god. Expert Review of Clinical Immunology 6: 875-8.
Nilsson B, Korsgren O, Lambris JD, Ekdahl KN. (2010). Can cells and biomaterials in therapeutic medicine be shielded from innate immune recognition? Trends in Immunology 31: 32-8.
Ricklin D, Hajishengallis G, Yang K, Lambris JD. (2010). Complement: a key system for immune surveillance and homeostasis. Nature Immunology 11: 785-97.
Krauss JL, Potempa J, Lambris JD, Hajishengallis G. (2009). Complementary Tolls in the periodontium: how periodontal bacteria modify complement and Toll-like receptor responses to prevail in the host. Periodontology 2000 52: 141-62.
Markiewski MM, DeAngelis RA, Lambris JD. (2009). Complexity of complement activation in sepsis. Journal of Cellular and Molecular Medicine 12: 2245-54.
Markiewski MM, Lambris JD. (2009). Unwelcome Complement. Cancer Research 69: 6367-70.
Markiewski MM, Lambris JD. (2009). Is complement good or bad for cancer patients? A new perspective on an old dilemma. Trends in Immunology 30: 286-92.
Qu H, Ricklin D, Lambris JD. (2009). Recent developments in low molecular weight complement inhibitors. Molecular Immunology 47: 185-95.
Amara U, Rittirsch D, Flierl M, Bruckner U, Klos A, Gebhard F, Lambris JD, Huber-Lang M.(2008). Interaction between the coagulation and complement system. Advances in Experimental Medicine and Biology 632: 71-9.
Lambris JD, Ricklin D, Geisbrecht BV. (2008). Complement evasion by human pathogens. Nature reviews Microbiology 6: 132-42.
Ricklin D, Lambris JD. (2008). Compstatin: a complement inhibitor on its way to clinical application. Advances in Experimental Medicine and Biology 632: 273-92.
Markiewski MM, Lambris JD. (2007). The role of complement in inflammatory diseases from behind the scenes into the spotlight. American Journal of Pathology 171: 715-727.
Markiewski MM, Nilsson B, Ekdahl KN, Mollnes TE, Lambris JD. (2007). Complement and coagulation: strangers or partners in crime? Trends in Immunology 28: 184-192.
Nilsson B, Ekdahl KN, Mollnes TE, Lambris JD. (2007). The role of complement in biomaterial-induced inflammation. Molecular Immunology 44 : 82-94.
Pinto MR, Melillo D, Giacomelli S, Sfyroera G, Lambris JD. (2007). Ancient origin of the complement system: Emerging invertebrate models. Adv Exp Med Biol 598: 372-388.
Ricklin D, Lambris JD. (2007). Exploring the complement interaction network using surface plasmon resonance. Adv Exp Med Biol 598: 260-278.
Ricklin D, Lambris JD. (2007). Complement-targeted therapeutics. Nature Biotechnology 25: 1265-75.
Schuster MC, Chen H, and Lambris JD. (2007). Hydrogen/Deuterium exchange mass spectrometry: Potential for investigating innate immunity proteins. Adv Exp Med Biol 598: 407-417.
Smith RJ, Alexander J, Barlow PN, Botto M, Cassavant TL, Cook HT, de Crdoba SR, Hageman GS, Jokiranta TS, Kimberling WJ, Lambris JD, Lanning LD, Levidiotis V, Licht C, Lutz HU, Meri S, Pickering MC, Quigg RJ, Rops AL, Salant DJ, Sethi S, Thurman JM, Tully HF, Tully SP, van der Vlag J, Walker PD, Wrzner R, Zipfel PF. (2007). New Approaches to the Treatment of Dense Deposit Disease. Journal of the American Society of Nephrology 18: 2447-2456.
DeAngelis RA, Markiewski MM, Lambris JD. (2006). Liver regeneration: a link to inflammation through complement. Advances in Experimental Medicine and Biology 586: 17-34.
Mastellos D, Lambris JD. (2006). Cross-disciplinary research stirs new challenges into the study of the structure, function and systems biology of complement. Advances in Experimental Medicine and Biology 586: 1-16.
Reca R, Wysoczynski M, Yan J, Lambris JD, Ratajczak MZ. (2006). The role of third complement component (C3) in homing of hematopoietic stem/progenitor cells into bone marrow. Advances in experimental medicine and biology 586: 35-51.
Tsonis PA, Lambris JD, Del Rio-Tsonis K. (2006). To regeneration...with complement. Advance in Experimental Medicine and Biology 586: 63-70.
Morikis D, Floudas CA, and Lambris JD. (2005). Structure-based integrative computational and experimental approach for the optimization of drug design. Computational Science - Iccs 2005, Pt 2 3515: 680-688.
Appel GB, Cook HT, Hageman G, Jennette JC, Kashgarian M, Kirschfink M, Lambris JD, Lanning L, Lutz HU, Meri S, Rose NR, Salant DJ, Sethi S, Smith RJ, Smoyer W, Tully HF, Tully SP, Walker P, Welsh M, Wrzner R, Zipfel PF. (2005). Membranoproliferative glomerulonephritis type II (dense deposit disease): an update. Journal of the American Society of Nephrology 16: 1392-403.
Markiewski MM, DeAngelis RA, Lambris JD. (2005). Liver inflammation and regeneration: two distinct biological phenomena or parallel pathophysiologic processes? Molecular Immunology 43: 45-56.
Mastellos D, Andronis C, Persidis A, Lambris JD. (2005). Novel biological networks modulated by complement. Clinical Immunology 115: 225-35.
Mastellos D, Germenis AE, Lambris JD. (2005). Complement: an inflammatory pathway fulfilling multiple roles at the interface of innate immunity and development. Current drug targets. Inflammation and allergy 4: 125-7.
Mastellos D, Lambris JD. (2005). Intergrating Innate Immunity into a Global 'Systems' Context: the Complement Paradigm Shift. Systems Biology.
Morikis D, Lambris JD. (2005). The building blocks of the complement system. The Structural Biology of the Complement System pp: 1-18.
Morikis D, Lambris JD. (2005). Structure, dynamics activity and function of compstatin and design of more potent analogs. The Structural Biology of the Complement System pp: 317-340.
Morikis D, Lambris JD. (2005). Structure of anaphylatoxins C3a and C5a. The Structural Biology of the Complement System pp: 161-178.
Floudas C A, Klepeis JL, Lambris JD, Morikis D. (2004). De Novo Protein Design" An Interplay of Global Optimization, Mixed-Integer Optimization and Experiments. Proceedings of FOCAPD pp: 133-146.
Holland MC, Morikis D, Lambris JD. (2004). Synthetic small-molecule complement inhibitors.Current Opinion in Investigational Drugs 5: 1164-73.
Holland MCH, Lambris JD. (2004). Complement. Nature Encyclopedia of Life Sciences.
Mastellos D, Morikis D, Strey C, Holland MC, Lambris JD. (2004). From atoms to systems: a cross-disciplinary approach to complement-mediated functions. Molecular Immunology 41: 153-64.
Morikis D, Lambris JD. (2004). Physical methods for structure, dynamics and binding in immunological research. Trends in Immunology 25: 700-7.
Morikis D, Soulika AM, Mallik B, Klepeis JL, Floudas CA, Lambris JD. (2004). Improvement of the anti-C3 activity of compstatin using rational and combinatorial approaches. Biochemical Society Transactions 32: 28-32.
Sarrias MR, Sahu A, Lambris JD. (2004). Characterization of the interactions of complement receptor 2 with its ligands iC3b,C3d and EBV glycoprotein gp350/220. Biacore Journal 4: 14-17.
Mastellos D, Morikis D, Isaacs SN, Holland MC, Strey CW, Lambris JD. (2003). Complement: structure, functions, evolution, and viral molecular mimicry. Immunologic Research 27: 367-86.
Morikis D, Lambris JD. (2002). Structural aspects and design of low-molecular-mass complement inhibitors. Biochemical Society Transactions 30: 1026-1036.
Holland MC, Lambris JD. (2002). The complement system in teleosts. Fish & Shellfish Immunology 12: 399-420.
Mastellos D, Lambris JD. (2002). Complement: more than a 'guard' against invading pathogens? Trends in Immunology 23: 485-91.
Mollnes TE, Song WC, Lambris JD.(2002). Complement in inflammatory tissue damage and disease. Trends in Immunology 23: 61-4.
Sahu A, Lambris JD. (2002). Novel anti-factor D monoclonal antibody inhibits complement and leukocyte activation in a baboon model of cardiopulmonary bypass - Invited commentary. Annals of Thoracic Surgery 74 (2): 362.
Sahu A, Lambris JD. (2001). Structure and biology of complement protein C3, a connecting link between innate and acquired immunity. Immunological Reviews 180: 35-48.
Zarkadis IK, Mastellos D, Lambris JD. (2001). Phylogenetic aspects of the complement system. Developmental and Comparative Immunology 25: 745-62.
Sahu A, Lambris JD. (2000). Complement inhibitors: a resurgent concept in anti-inflammatory therapeutics. Immunopharmacology 49: 133-48.
Sahu A, Morikis D, Lambris JD. (2000). Complement inhibitor targeting C3,C4, and C5. Therapeutic interventions in the complement system 4: 75-112.
Song WC, Sarrias MR, Lambris JD. (2000). Complement and innate immunity. Immunopharmacology 49: 187-98.
Lambris JD, Reid KB, Volanakis JE. (1999). The evolution, structure, biology and pathophysiology of complement. Immunology Today 20: 207-11.
Morikis D, Sahu A, Moore WT, Lambris JD. (1999). Design, structure, function and application of compstatin in Bioactive peptides in Drug discovery and design: medical aspects. IOS Press pp: 235-246.
Sunyer JO, Lambris JD. (1999). Evolution and diversity of the complement system of poikilothermic vertebrates. Immunological Reviews 166: 39-57.
Sunyer JO, Lambris JD (1999). Complement. Encyclopedia of Life Sciences.
Lambris JD, Sahu A, Wetsel RA. (1998). C3, C4 and C5: Genes, structure, and functions. The Human Complement System in Health and Disease pp: 83-118.
Sahu A, Sunyer JO, Moore WT, Sarrias MR, Soulika AM, Lambris JD. (1998). Structure, functions, and evolution of the third complement component and viral molecular mimicry. Immunologic Research 17: 109-21.
Sunyer JO, Zarkadis IK, Lambris JD. (1998). Complement diversity: a mechanism for generating immune diversity? Immunology Today 19: 519-23.
Lambris JD, Mavroidis M, Sunyer, JO. (1994). Phylogeny of third component of complement, C3. New Aspects of complement structure and function 2: 15-34.
Lambris, JD (1993). Chemistry, biology and phylogeny of C3. Complement Profiles 1: 16-45.
Lambris, JD, Becherer JD, Servis C, Alsenz J. (1993). Use of synthetic peptides in exploring and modifying complement reactivities. Activators and inhibitors of complement activation, Kluwer Academic Press, Lancaster pp: 201-232.
Tsoukas CD, Lambris JD. (1993). Expression of EBV/C3d receptors on T cells: biological significance.Immunology Today 14: 56-9.
Alsenz J, Becherer JD, Nilsson B, Lambris JD. (1990). Structural and functional analysis of C3 using monoclonal antibodies. Current Topics in Microbiology and Immunology 153: 235-48.
Becherer JD, Alsenz J, Lambris JD. (1990). Molecular aspects of C3 interactions and structural/functional analysis of C3 from different species. Current Topics in Microbiology and Immunology 153: 45-72.
Becherer JD, Alsenz J, Servis C, Myones BL, Lambris JD. (1989). Cell surface proteins reacting with activated complement components. Complement and Inflammation 6: 142-65.
Lambris JD. (1989). The multifunctional role of C3, the third component of complement. Immunology Today 9: 387-93.
Lambris JD, Mller-Eberhard HJ. (1987). The multifunctional role of C3: structural analysis of its interactions with physiological ligands. Molecular Immunology 23: 1237-42.
Lambris JD, Tsokos GC. (1986). The biology and pathophysiology of complement receptors. Anticancer Research 6: 515-23.